Anti-PKD2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss
BS-2158R-A555
BOSSBS-2158R-A555EA 893 EUR
BOSSBS-2158R-A555
Anti-PKD2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Antibodies
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of theMore Product Information
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