Anti-KCNQ1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss
BS-6760R-A488
BOSSBS-6760R-A488EA 890 EUR
BOSSBS-6760R-A488
Anti-KCNQ1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and otherMore Product Information
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