You Searched For: Antibodies

Catalog Number: (BOSSBS-1383R-A488)

Supplier: Bioss

Description: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-9776R-A750)

Supplier: Bioss

Description: C10orf140, also known as DLN-1, is an 827 amino acid protein that belongs to the DACH/dachshund family. C10orf140 contains a poly-Alanine region that is highly polymorphic. The gene encoding C10orf140 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

UOM: 1 * 100 µl

Catalog Number: (USBIK1778)

Supplier: US Biological

Description: Anti-Kindlin-2 Mouse Monoclonal Antibody [clone: 10H13]

UOM: 1 * 100 µG

Catalog Number: (BOSSBS-10200R-CY7)

Supplier: Bioss

Description: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

UOM: 1 * 100 µl

Catalog Number: (AVIVARP64238_P050)

Supplier: Aviva Systems Biology

Description: Anti-UNC5C Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

Catalog Number: (USBIN0800-03J-APC)

Supplier: US Biological

Description: Anti-NEK2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-6243R-FITC)

Supplier: Bioss

Description: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Catalog Number: (USBI135245)

Supplier: US Biological

Description: Anti-VGLL2 Mouse Polyclonal Antibody

UOM: 1 * 50 µG

Catalog Number: (USBI043254)

Supplier: US Biological

Description: Anti-TRIM59 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-6947R-FITC)

Supplier: Bioss

Description: KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-2210R-CY5.5)

Supplier: Bioss

Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-1688R)

Supplier: Bioss

Description: Hsp20 is a small heat shock protein related to Hsp25, Hsp27 and may form different hetercomplexes with these proteins. The specific physiological function of Hsp20 is not yet known. It is distributed ubiquitously in tissues, but is found in higher levels in skeletal, smooth and heart muscle. Under normal conditions, Hsp20 is diffusely distributed in the cytosol, but under heat stress conditions, it translocates to the nucleus. Unlike other heat shock proteins the amount of Hsp20 does not increase after heat shock. The Hsp20 was demonstrated to constitute up to 1.3% of the total cellular protein in vertebrate tissues, especially in muscle, and its expression is related to muscle contraction, specifically in slow-twitch muscle. Hsp20 may form different heterocomplexes with other Hsp's, such as alpha-crystalline and Hsp25. Phosphorylated form of Hsp20 is proposed to interact with monomeric actin whereas dephosphorylated form binds polymeric actin filaments. In normal conditions Hsp20 is diffusely disturbed in cytosol but under the heat stress it undergoes translocation to membrane fraction.

UOM: 1 * 100 µl

Catalog Number: (USBIU1000-86V)

Supplier: US Biological

Description: Anti-UBE2D2 Mouse Monoclonal Antibody [clone: 4A1]

UOM: 1 * 50 µG

Supplier: Biotium

Description: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Catalog Number: (USBIB1200-03-AP)

Supplier: US Biological

Description: Anti-BIN3 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-8675R-A555)

Supplier: Bioss

Description: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

UOM: 1 * 100 µl