Anti-TIMP3 Rabbit Polyclonal Antibody (CF405S) [clone: Rabbit PAb]

Supplier: Biotium
BNC040408-500 BNC040408-100
BNC040408-500EA 560 EUR
BNC040408-500 BNC040408-100
Anti-TIMP3 Rabbit Polyclonal Antibody (CF405S) [clone: Rabbit PAb]
Antibodies
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Type: Primary
Antigen: TIMP3
Clonality: Polyclonal
Clone: Rabbit PAb
Conjugation: CF405S
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Cow, Dog, Horse, Human, Mouse, Rat
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