Pinometostat (EPZ-5676) ≥98%
Supplier: CAYMAN
16175-10
16175-1
16175-25
16175-5
CAYM16175-10EA
451
EUR
CAYM16175-10
CAYM16175-1
CAYM16175-25
CAYM16175-5
Pinometostat (EPZ-5676) ≥98%
Pinometostat (EPZ-5676)
EPZ5676 is a highly potent aminonucleoside inhibitor of DOT1 l histone methyltransferase activity (Ki = 80 pM) that demonstrates 37000-fold selectivity over other methyltransferases.
It can selectively inhibit the proliferation of acute leukemia cell lines bearing MLL translocations (IC50s range from 3.5 nM - 1.3 µM).
Formula:
C₃₀H₄₂N₈O₃ Storage Temperature: Freezer |
MDL Number:
MFCD24849415 CAS Number: 1380288-87-8 |
Specification Test Results
Purity | ≥98% |
Formulation | A Crystalline Solid |
λmax | 255 nm |
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