Pinometostat (EPZ-5676) ≥98%

Supplier: CAYMAN

16175-10 16175-1 16175-25 16175-5
CAYM16175-10EA 451 EUR
CAYM16175-10 CAYM16175-1 CAYM16175-25 CAYM16175-5
Pinometostat (EPZ-5676) ≥98%
Pinometostat (EPZ-5676)

EPZ5676 is a highly potent aminonucleoside inhibitor of DOT1 l histone methyltransferase activity (Ki = 80 pM) that demonstrates 37000-fold selectivity over other methyltransferases.


It can selectively inhibit the proliferation of acute leukemia cell lines bearing MLL translocations (IC50s range from 3.5 nM - 1.3 µM).

Formula: C₃₀H₄₂N₈O₃
Storage Temperature: Freezer
MDL Number: MFCD24849415
CAS Number: 1380288-87-8

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Specification Test Results

Purity ≥98%
Formulation A Crystalline Solid
λmax 255 nm


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