BI-605906 ≥98%

Supplier: CAYMAN

19184-1 19184-5
CAYM19184-1EA 124 EUR
CAYM19184-1 CAYM19184-5
BI-605906 ≥98%
BI-605906

  • An IKKβ inhibitor


An IKKβ inhibitor (IC50 = 380 nM); selective for IKKβ over insulin-like growth factor 1 (IGF1; IC50 = 7.6 μM) and over 100 kinases in a panel up to 10 μM; partially inhibits IL-1-stimulated activation of IKKε/TBK1 in vitro; inhibits TNF-α-dependent IkB degradation and expression of the proinflammatory cytokines IL-6, IL-1β, and CXCL1/2 without affecting lipogenic gene expression or glucose production in murine primary hepatocytes

Formula: C₁₇H₂₂F₂N₄O₃S₂
Storage Temperature: Freezer
CAS Number: 960293-88-3

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Specification Test Results

Formulation A crystalline solid
Purity ≥98%
Stability ≥ 2 years


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