Anti-CD43 Mouse Monoclonal Antibody [clone: CD43-10G7] (PE)

Supplier: STEMCELL TECHNOLOGIES
60085PE 60085PE.1
STMC60085PEEA 0 EUR
STMC60085PE STMC60085PE.1
Anti-CD43 Mouse Monoclonal Antibody [clone: CD43-10G7] (PE)
Antibodies
Mouse monoclonal IgG1 antibody against human CD43, PE-conjugated.

  • B cells

The CD43-10G7 antibody reacts with human CD43, a type I transmembrane sialoglycoprotein expressed on the surface of most human hematopoietic cells, including thymocytes, peripheral T cells, NK cells, monocytes, granulocytes, some B cells (activated B cells and an early B cell subset in bone marrow), plasma cells, and hematopoietic progenitor cells. Low expression levels are observed on platelets. CD43 exhibits different glycoforms in the range of ~95 to 135 kDa, depending on the cell type. It binds ligands such as CD54 and CD169 (Siglec-1) and plays regulatory roles in cell adhesion and activation, apoptosis and tumor progression, and is used a marker for discriminating normal from neoplastic T cells and B cells within tissues. Binding of the CD43-10G7 antibody to CD43 on neutrophils reportedly induces homotypic cell adhesion.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-CD43 Mouse Monoclonal Antibody [clone: CD43-10G7] (PE)
Antigen: CD43
Clonality: Monoclonal
Clone: CD43-10G7
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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