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Catalog Number: (ABCAAB216563-100)
Supplier: Abcam
Description: Anti-Metabotropic Glutamate Receptor 2/MGLUR2 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (BOSSBS-1894R-A680)
Supplier: Bioss
Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13494R-HRP)
Supplier: Bioss
Description: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13494R-CY5)
Supplier: Bioss
Description: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
UOM: 1 * 100 µl


Catalog Number: (ABCAAB194909-100)
Supplier: Abcam
Description: Anti-Glutamate Receptor 1 (AMPA subtype) (phospho S836) Rabbit Polyclonal Antibody
UOM: 1 * 100 µl

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (BOSSBS-12009R-A680)
Supplier: Bioss
Description: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localised with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterised by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilon 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1161R-A750)
Supplier: Bioss
Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilisation.
UOM: 1 * 100 µl


Catalog Number: (BLDPBD18359-5G)
Supplier: BLD PHARMATECH GMBH
Description: Fmoc-Glu-OAll 97%
UOM: 1 * 5 g


Catalog Number: (BOSSBS-1003R-A750)
Supplier: Bioss
Description: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
UOM: 1 * 100 µl


Catalog Number: (ABCAAB109450-100)
Supplier: Abcam
Description: Anti-Glutamate Receptor 1 (AMPA subtype) Rabbit Monoclonal Antibody [clone: EPR5479]
UOM: 1 * 100 µl

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (BOSSBS-13494R-A750)
Supplier: Bioss
Description: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
UOM: 1 * 100 µl


Catalog Number: (ABCAAB192760-100)
Supplier: Abcam
Description: Anti-Ionotropic Glutamate receptor 2 Mouse Monoclonal Antibody [clone: L21/32]
UOM: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Supplier: Alfa Aesar
Description: Fmoc-Glu(OAll)-OH 95%

Catalog Number: (BOSSBS-13391R-FITC)
Supplier: Bioss
Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-10042R-A750)
Supplier: Bioss
Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitises rapidly and enters a transient inactive state, characterised by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitisation which is characterised by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-10042R-A680)
Supplier: Bioss
Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterised by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterised by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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