You Searched For: 15-Hydroxypentadecanoic+acid

Catalog Number: (BOSSBS-6505R-A555)

Supplier: Bioss

Description: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-6505R-HRP)

Supplier: Bioss

Description: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

UOM: 1 * 100 µl

Supplier: APOLLO SCIENTIFIC

Description: 2-Fluoro-4-biphenylboronic acid pinacol ester 98%

Supplier: APOLLO SCIENTIFIC

Description: Ethyl-3-aminopicolinate 98%

Catalog Number: (APOSBIP0687-50MG)

Supplier: APOLLO SCIENTIFIC

Description: Indefinitely stable at -15°C

UOM: 1 * 50 mg

Supplier: APOLLO SCIENTIFIC

Description: Methyl-5-bromopicolinate

Catalog Number: (BOSSBS-6505R-A680)

Supplier: Bioss

Description: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerisation which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

UOM: 1 * 100 µl

Supplier: AGILENT

Description: The Brilliant HRM Ultra-Fast Loci Master Mix for High Resolution Melt (HRM) analysis.

Supplier: APOLLO SCIENTIFIC

Description: 1-tert-Butylpyrazole-4-boronic acid, pinacol ester 97%

Catalog Number: (BLDPBD135950-25G)

Supplier: BLD PHARMATECH GMBH

Description: 2-Chloroethyl laurate 97%

UOM: 1 * 25 g

Catalog Number: (ACRO333110100)

Supplier: Thermo Scientific

Description: Appearance: Colorless to light yellow Solution

UOM: 1 * 10 mL

Supplier: APOLLO SCIENTIFIC

Description: 1-Methyl-5-(thien-2-yl)-1H-pyrazole-3-carboxylic acid 97%

Catalog Number: (8.16113.0100)

Supplier: Merck

Description: Triallyl isocyanurate for synthesis, Sigma-Aldrich®

UOM: 1 * 100 g

Catalog Number: (X0550-100)

Supplier: BIOWEST

Description: L(+)-Glutamine 0.2 mol/l in aqueous solution

UOM: 1 * 100 mL

MSDS

Supplier: Heraeus

Description: Increase nucleic acid sample separation by using the Thermo Scientific™ 10×5 ml rotor with ClickSeal™ biocontainment lid.

Supplier: VWR Chemicals

Description: This fast extract genotyping PCR kit consists of a fast extraction DNA solution and VWR® Red Taq DNA polymerase 2X master mix. It is ideal for genotyping of DNA extracted from mammalian tissues, plant material, saliva or bacteria, providing PCR-ready DNA in 8 minutes and genotyping results in less than 1,5 hours.