You Searched For: u0143

Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.

Catalog Number: BOSSBS-7720R-CY3

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.

Catalog Number: BOSSBS-7720R-CY7

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Catalog Number: BOSSBS-2745R-HRP

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Catalog Number: BOSSBS-2745R-A555

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Catalog Number: BOSSBS-2745R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

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Description: GLX351322 is an inhibitor of NADPH oxidase 4, inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M.

Catalog Number: APOSBISN0056-5MG

UOM: 1 * 5 mg

Supplier: APOLLO SCIENTIFIC

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Description: Purity determined enzymatic method (ADH).

Catalog Number: APOSBIB5006-50MG

UOM: 1 * 50 mg

Supplier: APOLLO SCIENTIFIC

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Description: Tris(2,4,6-trimethylphenyl)phosphine ≥98%

Catalog Number: B21116.06

UOM: 1 * 5 g

Supplier: Alfa Aesar

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Description: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

Catalog Number: BOSSBS-3216R

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Fatty acid synthetase catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

Catalog Number: BOSSBS-1498R-A555

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Fatty acid synthetase catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

Catalog Number: BOSSBS-1498R-FITC

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Fatty acid synthetase catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

Catalog Number: BOSSBS-1498R-A350

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.

Catalog Number: BOSSBS-7720R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases. Belongs to the histone deacetylase family.

Catalog Number: BOSSBS-5387R-FITC

UOM: 1 * 100 µl

Supplier: Bioss

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Description: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T1, also known as GALNT1 (Polypeptide N-acetylgalactosaminyltransferase 1), is a ubiquitously expressed 559 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and, like other GalNAc-Ts, contains a stem region and a C-terminal ricin/lectin-like domain. GalNAc-T1 catalyzes the first reaction in O-linked oligosaccharide biosynthesis, namely the transfer of an N-acetyl-D-galactosamine residue to a protein acceptor. GalNAc-T1 uses calcium and manganese as cofactors. Due to alternative splicing events, two GalNAc-T1 isoforms are expressed.

Catalog Number: BOSSBS-13273R-FITC

UOM: 1 * 100 µl

Supplier: Bioss

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Description: 5-(N-2-3-Dihydroxypropylacetimido)-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide

Catalog Number: 466650250.

UOM: 1 * 25 g

Supplier: Thermo Scientific

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