You Searched For: 2-Amino-4-chloro-5-fluoropyrimidine

Supplier: Biotium

Description: This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Supplier: Biotium

Description: This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Supplier: Biotium

Description: This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Supplier: Biotium

Description: This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Catalog Number: (8.02641.0250)

Supplier: Merck

Description: 5-Chloro-o-toluidine for synthesis, Sigma-Aldrich®

UOM: 1 * 250 mL

Supplier: Merck

Description: 3-Chloro-4-fluoroaniline for synthesis, Sigma-Aldrich®

Supplier: APOLLO SCIENTIFIC

Description: 3-Amino-2-chloro-6-methylphenol

Catalog Number: (APOSOR52200-25G)

Supplier: APOLLO SCIENTIFIC

Description: 3-Amino-2-chloro-6-methylpyridine 96%

UOM: 1 * 25 g

Catalog Number: (APOSOR110320-1G)

Supplier: APOLLO SCIENTIFIC

Description: 2-Amino-5-chloro-4-methylnicotinonitrile

UOM: 1 * 1 g

Catalog Number: (APOSPC0492-100G)

Supplier: APOLLO SCIENTIFIC

Description: 2-Amino-5-chloro-2'-fluorobenzophenone

UOM: 1 * 100 g

Catalog Number: (APOSOR5767-5G)

Supplier: APOLLO SCIENTIFIC

Description: 2-Amino-2'-chloro-5-nitrobenzophenone

UOM: 1 * 5 g

Catalog Number: (H61465.06)

Supplier: Alfa Aesar

Description: 3-Amino-6-chloro-2-methylpyridine 95%

UOM: 1 * 5 g

MSDS Certificates

Catalog Number: (APOSOR110378-25G)

Supplier: APOLLO SCIENTIFIC

Description: 2-Amino-5-chloro-3-iodopyridine

UOM: 1 * 25 g

Supplier: APOLLO SCIENTIFIC

Description: 2-Amino-6-chloro-3-methylquinoline

Catalog Number: (APOSOR13236-25G)

Supplier: APOLLO SCIENTIFIC

Description: 2-Amino-6-chloro-4-nitrophenol 97%

UOM: 1 * 25 g

Catalog Number: (H58501.06)

Supplier: Alfa Aesar

Description: 2-Amino-5-chloro-6-methylpyridine 97%

UOM: 1 * 5 g

MSDS