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Image Unavailable-BOSSBS-8328R-A350

Anti-PP4R3B Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-8328R-A350)
Supplier: Bioss
Description: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5020R-FITC

Anti-SOAT2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-5020R-FITC)
Supplier: Bioss
Description: Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6480R-HRP

Anti-CH25H Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6480R-HRP)
Supplier: Bioss
Description: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1698R-CY5

Anti-ox-LDL Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1698R-CY5)
Supplier: Bioss
Description: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1698R

Anti-ox-LDL Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-1698R)
Supplier: Bioss
Description: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.
UOM: 1 * 100 µl
Product Image-MODU378213

Safety blood lancets, VITREX® STERILANCE® Lite III

Supplier: Vitrex Medical A/S
Description: Safety lancets for blood glucose and other<i> in vitro</i> diagnostic tests.

Image Unavailable-BOSSBS-3862R-CY5.5

Anti-SCAP Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-3862R-CY5.5)
Supplier: Bioss
Description: SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11426R-CY3

Anti-FDX1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11426R-CY3)
Supplier: Bioss
Description: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13687R

Anti-LAMTOR1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13687R)
Supplier: Bioss
Description: Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5013R

Anti-ABCG5 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5013R)
Supplier: Bioss
Description: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11549R-HRP

Anti-DISP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11549R-HRP)
Supplier: Bioss
Description: Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3919R

Anti-STARD5 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-3919R)
Supplier: Bioss
Description: STARD5, or START domain containing 5, belongs to a family containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain. STARD5 may be involved in the intracellular transport of sterols or other lipids and may bind cholesterol or other sterols.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4063R-A555

Anti-HMGCR Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-4063R-A555)
Supplier: Bioss
Description: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5068R-FITC

Anti-HMGCR Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-5068R-FITC)
Supplier: Bioss
Description: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-CY3

Anti-CYP39A1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5050R-CY3)
Supplier: Bioss
Description: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10130R-A750

Anti-APOD Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-10130R-A750)
Supplier: Bioss
Description: APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 88 22222.
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