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Description: Ascorbyl Palmitate, NF is often used to promote flow of tableting powders and to prevent their sticking in tablet presses.
Catalog Number: SPCMA1372-50KGBL
UOM: 1 * 50 kg
Supplier: Spectrum Chemical


Description: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Catalog Number: BOSSBS-20595R-A680
UOM: 1 * 100 µl
Supplier: Bioss


Description: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Catalog Number: BOSSBS-20595R-A750
UOM: 1 * 100 µl
Supplier: Bioss


Description: 6-O-Palmitoyl-L-ascorbic acid 98.0-100.5%, EMPROVE® ESSENTIAL Ph. Eur., BP, NF, FCC, E304, SAFC®
Catalog Number: 5.00090.2500
UOM: 1 * 2,5 kg
Supplier: MERCK PRODUCTION CHEMICALS


Description: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Catalog Number: BOSSBS-20594R-A750
UOM: 1 * 100 µl
Supplier: Bioss


Description: High quality inorganic and organic reference materials produced according to ISO 9001.
Catalog Number: HONCR1483-10MG
UOM: 1 * 10 mg
Supplier: Honeywell Chemicals


Description: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Catalog Number: BOSSBS-20594R-A680
UOM: 1 * 100 µl
Supplier: Bioss


Description: Glycidyl isopropyl ether for synthesis
Catalog Number: 8.18598.2500
UOM: 1 * 2,5 L
Supplier: Merck


Description: Isopropyl myristate for synthesis, Sigma-Aldrich®
Catalog Number: 8.22102.0100
UOM: 1 * 100 mL
Supplier: Merck


Description: Isopropyl 2-bromo-2-methylpropionate zS, Sigma-Aldrich®
Catalog Number: 8.14785.0025
UOM: 1 * 25 mL
Supplier: Merck


Description: 5-Isopropyl-2-methylphenol, Sigma-Aldrich®
Catalog Number: 8.20258.0250
UOM: 1 * 250 mL
Supplier: Merck


Description: Isopropyl acetate, Supelco®
Catalog Number: 90871-5ML-F
UOM: 1 * 5 mL
Supplier: Merck


Description: Isopropyl acetate for synthesis, Sigma-Aldrich®
Catalog Number: 8.20560.0100
UOM: 1 * 100 mL
Supplier: Merck


Description: Isopropyl myristate ≥98%, GPR RECTAPUR®
Catalog Number: 85991.320
UOM: 1 * 2,5 L
Supplier: VWR Chemicals

Description: Isopropyl acetate ≥99%, GPR RECTAPUR®
Catalog Number: 87068.320
UOM: 1 * 2,5 L
Supplier: VWR Chemicals

Description: IPTG (isopropyl-β-D-thiogalactopyranoside) ≥99%, Ultrapure
Catalog Number: J436-100G
UOM: 1 * 100 g
Supplier: VWR Chemicals


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