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Supplier: Merck
Description: EDTA disodium salt dihydrate 99.0-101.0% (by titrimetric analysis) for HPLC, Supelco®

Supplier: Merck
Description: For analysis for the determination of ascorbic acid

Supplier: Merck
Description: Titriplex® IV (trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid monohydrate) analytical reagent, Supelco®

Supplier: Merck
Description: EDTA dipotassium salt dihydrate analytical reagent, Supelco®

Supplier: Hach
Description: These are used for determination of Ultra Low Range silica by the Heteropoly Blue Rapid Liquid method. Rapid Liquid™ methods offer an economical way to analyse multiple samples and to measure trace concentrations.

Supplier: Thermo Scientific
Description: EDTA disodium salt dihydrate 99+% for analysis

Supplier: Thermo Scientific
Description: Bicine 99+% for analysis
Supplier: Merck
Description: Titriplex® III ACS, ISO, Reag. Ph. Eur. analytical reagent, Supelco®

Supplier: Thermo Scientific
Description: Thermo Scientific™ cell culture media for SILAC is optimised for use with stable isotope labeling with amino acids in cell culture (SILAC) to analyse protein expression by mass spectrometry (MS).

Supplier: PERKIN ELMER GC INSTRUMENTS
Description: Strong Cation Exchange (SCX) Supra-Clean® spherical silica-based SPE columns are recommended for extracting basic compounds when analysing cations, antibiotics, drugs, amino acids, catecholamines, herbicides, nucleic acid bases, nucleosides and surfactants.

Catalog Number: (BSENM-1586-100)
Supplier: Biosensis
Description: The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively. MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice). Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.
UOM: 1 * 100 µG


Catalog Number: (20490.188)
Supplier: VWR Chemicals
Description: EDTA dipotassium salt dihydrate ≥97.0% analytical reagent
UOM: 1 * 100 g

Supplier: TOSOH Bioscience
Description: These silica- and polymer-based columns are ideal for reversed-phase applications such as pharmaceutical drugs, forensic compounds, derivatised amino acids, carbohydrates, steroids, lipids and fatty acids. Depending on their molecular weight, peptides may be analysed with the 80 to 140 Å silica-based columns, while proteins require a larger pore size column (200 to 300 Å).

Supplier: VWR Chemicals
Description: EDTA disodium salt dihydrate 99.0-101.0%, AnalaR NORMAPUR® ACS, Reag. Ph. Eur. analytical reagent
Catalog Number: (BSENM-1742-50-B)
Supplier: Biosensis
Description: The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively.

MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice).

Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.

Biosensis now offers biotinylated MOAB-2 antibody allowing more flexibility in experimental design by using the biotin-avidin/streptavidin detection method. Biotinylated MOAB-2 antibody may also help to reduce background staining in difficult-to-stain tissues and increase detection sensitivity. The ability of biotinylated MOAB-2 antibody to detect amyloid beta has been validated by IHC.
UOM: 1 * 50 µG


Catalog Number: (1.08310.0250)
Supplier: Merck
Description: o-Toluidine analytical reagent, Supelco®
UOM: 1 * 250 mL


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 88 22222.
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