You Searched For: N-Carbobenzoxy-6-aminohexanoic+acid

Description: TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing.The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Catalog Number: PRSI29-459

UOM: 1 * 50 µG

Supplier: ProSci Inc.

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Description: A chromogenic β-lactamase substrate that undergoes distinctive color change from yellow (λmax = 390 nm at pH 7.0) to red (λmax = 486 nm at pH 7.0) as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase

Catalog Number: 484400-5MG

UOM: 1 * 5 mg

Supplier: Merck Millipore (Calbiochem‎)

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Description: MDA5 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the melanoma differentiation-associated protein 5 (MDA5) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. MDA5, a member of the DEAD/DEAH-box RNA helicase family, consists of an amino-terminal caspase recruitment domain (CARD) and a carboxyl-terminal RNA helicase domain similar to that of the related protein RIG-1. When stimulated by dsRNA, MDA5 recruits the adaptor protein VISA and ultimately causes the activation of IRF-3 and NF-kappa B. MDA5 and RIG-1 recognize different types of dsRNA, with MDA5 recognizing poly (I:C). MDA5-null mice were highly susceptible to infection with picornaviruses, which possess such sequences, demonstrating the importance of MDA5 in innate immunity.

Catalog Number: PRSI4037

UOM: 1 * 100 µG

Supplier: ProSci Inc.

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Description: MDA5 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the melanoma differentiation-associated protein 5 (MDA5) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. MDA5, a member of the DEAD/DEAH-box RNA helicase family, consists of an amino-terminal caspase recruitment domain (CARD) and a carboxyl-terminal RNA helicase domain similar to that of the related protein RIG-1. When stimulated by dsRNA, MDA5 recruits the adaptor protein VISA and ultimately causes the activation of IRF-3 and NF-kappa B. MDA5 and RIG-1 recognize different types of dsRNA, with MDA5 recognizing poly (I:C). MDA5-null mice were highly susceptible to infection with picornaviruses, which possess such sequences, demonstrating the importance of MDA5 in innate immunity.

Catalog Number: PRSI4039

UOM: 1 * 100 µG

Supplier: ProSci Inc.

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Description: T-Cell Intracellular Antigen-1 is a cytoplasmic granule-associated protein expressed in lymphocytes processing cytolytic potential. It is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognises poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15 kDa protein thought to be derived from the carboxyl terminus of the 40 kDa product by proteolytic processing. TIA-1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies.

Catalog Number: PRSI34-055

UOM: 1 * 100 µG

Supplier: ProSci Inc.

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Description: Bond Elut™ SAX is a strong anion exchange sorbent ideally suited for the extraction of compounds such as carboxylic acids, which may not retain effectively on weak anion exchange sorbents. The sorbent is supplied in the chloride counter ion form. You can modify the selectivity of the phase by replacing the chloride ion with other anions, such as acetate and hydroxide.

Catalog Number: 551-0348

UOM: 1 * 50 items

Supplier: VARIAN

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Description: Sera-Mag Select PCR clean-up, size selection reagent combines the exceptional binding characteristics of Sera-Mag carboxyl speedbeads with an optimised binding solution in a ready to use formulation. The DNA size range isolated from the process can be tailored to suit the user’s end requirements by adjusting the amount of reagent that is mixed with a fixed volume of sample.

Catalog Number: 29-3430-52

UOM: 1 * 60 mL

Supplier: Cytiva

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Description: Poly(styrene-divinylbenzene), microspheres 6.0-10.0 μm avg. part. size, Supelco®

Catalog Number: 468312-250G

UOM: 1 * 250 g

Supplier: Merck

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Description: Poly(methyl hydrogen siloxane) for synthesis, Sigma-Aldrich®

Catalog Number: 8.18063.0250

UOM: 1 * 250 mL

Supplier: Merck

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Description: Vinyl acetate

Catalog Number: 48486.

UOM: 1 * 1 items

Supplier: Merck

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Description: Butyl vinyl ether stabilised for synthesis, Sigma-Aldrich®

Catalog Number: 8.01847.0500

UOM: 1 * 500 mL

Supplier: Merck

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Description: Vinyl acetate stabilised for synthesis, Sigma-Aldrich®

Catalog Number: 8.03184.0100

UOM: 1 * 100 mL

Supplier: Merck

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Description: Poly-4-vinylpyridinium poly(hydrogen fluoride)

Catalog Number: APOSPC6267G-25G

UOM: 1 * 25 g

Supplier: APOLLO SCIENTIFIC

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Description: 1-Vinyl-2-pyrrolidone stabilised for synthesis, Sigma-Aldrich®

Catalog Number: 8.08518.0005

UOM: 1 * 5 mL

Supplier: Merck

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Description: Ethyl vinyl ether stabilised, Sigma-Aldrich®

Catalog Number: 8.01391.9040

UOM: 1 * 40 kg

Supplier: Merck

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Description: Poly-(L-lysine) 95%

Catalog Number: BLDPBD148593-25G

UOM: 1 * 25 g

Supplier: BLD PHARMATECH GMBH

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