You Searched For: Nicotinic+acid+N-oxide

Description: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.

Catalog Number: BOSSBS-12501R-A350

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: STARD5, or START domain containing 5, belongs to a family containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain. STARD5 may be involved in the intracellular transport of sterols or other lipids and may bind cholesterol or other sterols.

Catalog Number: BOSSBS-3919R-A350

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: HSL/LIPE is found in adipose tissue and heart, where it primarily hydrolyzes stored triglycerides to free fatty acids. It is also found in steroidogenic tissues, where it principally converts cholesteryl esters to free cholesterol for steroid hormone production. There are two named isoforms.

Catalog Number: BOSSBS-3223R-A647

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Catalog Number: BOSSBS-3608R-A488

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.

Catalog Number: BOSSBS-11426R-CY7

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

Catalog Number: BOSSBS-6277R-A750

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol.

Catalog Number: BOSSBS-8328R-FITC

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol.

Catalog Number: BOSSBS-8328R-A647

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.

Catalog Number: BOSSBS-5020R-A555

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol.

Catalog Number: BOSSBS-8328R-A555

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Functions in hedgehog (Hh) Signalling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.

Catalog Number: BOSSBS-11549R-A750

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.

Catalog Number: BOSSBS-11549R-A350

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.

Catalog Number: BOSSBS-11549R-A555

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Catalog Number: BOSSBS-5068R-A488

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Catalog Number: BOSSBS-5068R-A555

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.

Catalog Number: BOSSBS-3862R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

Sale