You Searched For: Dexamethasone

Catalog Number: (EDQMD0720000)

Supplier: EDQM

Description: Filled under inert atmosphere protected from humidity.

UOM: 1 * 130 mg

Catalog Number: (PRSI91-661)

Supplier: ProSci Inc.

Description: 15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.

UOM: 1 * 50 µG

Catalog Number: (PRSI29-080)

Supplier: ProSci Inc.

Description: NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. NR1I2 contains a zinc finger domain.NR1I2 is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. The gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. The gene product contains a zinc finger domain. Three alternatively spliced transcripts that encode different isoforms have been described, one of which encodes two products through the use of alternative translation initiation codons. Additional transcript variants derived from alternative promoter usage, alternative splicing, and/or alternative polyadenylation exist, but they have not been fully described.

UOM: 1 * 100 µG

Catalog Number: (PRSI25-312)

Supplier: ProSci Inc.

Description: NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. NR1I2 contains a zinc finger domain.NR1I2 is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

UOM: 1 * 50 µG

Catalog Number: (PRSI29-121)

Supplier: ProSci Inc.

Description: NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. NR1I2 contains a zinc finger domain.NR1I2 is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain.The gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. The gene product contains a zinc finger domain. Three alternatively spliced transcripts that encode different isoforms have been described, one of which encodes two products through the use of alternative translation initiation codons. Additional transcript variants derived from alternative promoter usage, alternative splicing, and/or alternative polyadenylation exist, but they have not been fully described.

UOM: 1 * 100 µG

Catalog Number: (PRSI5303)

Supplier: ProSci Inc.

Description: ABIN3 Antibody: The nuclear factor NF-kappa B plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kappa B activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kappa B activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kappa B activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kappa B inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kappa B in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.

UOM: 1 * 100 µG

Catalog Number: (CAYM10008980-1)

Supplier: Cayman Chemical

Description: Adipogenesis Assay Dexamethasone Solution 1000X 1 * 1 items

UOM: 1 * 1 items

Catalog Number: (CAYM20340-1)

Supplier: Cayman Chemical

Description: Dexamethasone Phosphate (sodium salt) 1 * 1 g

UOM: 1 * 1 g

Catalog Number: (CAYM20340-5)

Supplier: Cayman Chemical

Description: Dexamethasone Phosphate (sodium salt) 1 * 5 g

UOM: 1 * 5 g

Catalog Number: (ABCAAB142419-100)

Supplier: Abcam

Description: DEXAMETHASONE SODIUM PHOSPHATE 1 * 100 mg

UOM: 1 * 100 mg

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Catalog Number: (1A00340)

Supplier: USP

Description: DEXAMETHASONE ETHYL ESTER 1 * 25 mg

UOM: 1 * 25 mg

Catalog Number: (CAYM10009950-1)

Supplier: Cayman Chemical

Description: Adipolysis Assay Dexamethasone Solution 1000X 1 * 1 items

UOM: 1 * 1 items

Catalog Number: (CAYM20340-500)

Supplier: Cayman Chemical

Description: Dexamethasone Phosphate (sodium salt) 1 * 500 mg

UOM: 1 * 500 mg

Catalog Number: (CAYM22100-5)

Supplier: Cayman Chemical

Description: Dexamethasone-d4 1 * 5 mg

UOM: 1 * 5 mg

Catalog Number: (CAYM22100-10)

Supplier: Cayman Chemical

Description: Dexamethasone-d4 1 * 10 mg

UOM: 1 * 10 mg

Catalog Number: (CAYM22286-100)

Supplier: Cayman Chemical

Description: Dexamethasone Acetate 1 * 100 mg

UOM: 1 * 100 mg