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Catalog Number: (BOSSBS-13046R-A488)
Supplier: Bioss
Description: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13046R-A680)
Supplier: Bioss
Description: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13046R-A350)
Supplier: Bioss
Description: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
UOM: 1 * 100 µl


Supplier: MP Biomedicals
Description: Succinylsulphathiazole

Catalog Number: (PRSI27-204)
Supplier: ProSci Inc.
Description: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO (2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
UOM: 1 * 50 µG


Catalog Number: (MOLEM70336609)
Supplier: Molekula
Description: Butyrylthiocholine chloride
UOM: 1 * 1 g

Market Source Item This is a MarketSource item. Additional charges may apply

Supplier: MP Biomedicals
Description: E-64 is an inhibitor for thiol protease, papain, actinidin, ananain, bromelain, calpain and cathepsin B. An irreversible cysteine protease inhibitor that has no action on cysteine residues in other plants. It does not react with low molecular weight thiols such as 2-mercaptoethanol.

Catalog Number: (J63270.MA)
Supplier: Alfa Aesar
Description: Calmidazolium chloride
UOM: 1 * 10 mg


Catalog Number: (PRSI26-853)
Supplier: ProSci Inc.
Description: Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
UOM: 1 * 50 µG


Supplier: Alfa Aesar
Description: Ethyl violet

Catalog Number: (MOLE61538581-1G)
Supplier: Molekula
Description: Acetylthiocholine chloride
UOM: 1 * 1 g

Market Source Item This is a MarketSource item. Additional charges may apply

Supplier: MP Biomedicals
Description: Succinic acid is a dicarboxylic acid that occurs in nature in such organisms as fungi and lichens. In eukaryotes, succiniate, the anion of succinic acid, is an intermediate in the citric acid cycle, being formed from succinyl CoA and being converted to fumarate. Bacteria and plants can produce succinate from acetate or acetyl CoA, in the glyoxylate cycle.

Supplier: Alfa Aesar
Description: Methyl green zinc chloride salt

Catalog Number: (MOLEM31140436)
Supplier: Molekula
Description: Methyl green zinc chloride salt
UOM: 1 * 25 g

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (ICNA0215801625)
Supplier: MP Biomedicals
Description: Ethyl violet is a cationic triarylmethane dye that is the ethyl homolog of crystal violet. It is a general histological and pathological stain.
UOM: 1 * 25 g


Catalog Number: (TREV4800-30-18)
Supplier: TREVIGEN
Description: Methyl green zinc chloride salt 1% aqueous solution
UOM: 1 * 50 mL

Market Source Item This is a MarketSource item. Additional charges may apply

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
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