You Searched For: Fmoc-2,4-dichloro-L-phenylalanine

Catalog Number: (BOSSBS-12941R)

Supplier: Bioss

Description: All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12942R-CY3)

Supplier: Bioss

Description: All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.

UOM: 1 * 100 µl

Supplier: Thermo Scientific

Description: α,4-Dichloro-2-nitrotoluene 98%

Catalog Number: (BOSSBS-12942R-A680)

Supplier: Bioss

Description: All members of the Src gene family of tyrosine kinases are characterised by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5 to 10 fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12941R-HRP)

Supplier: Bioss

Description: All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.

UOM: 1 * 100 µl

Supplier: APOLLO SCIENTIFIC

Description: 7,8-Dichloro-4-quinolinol

Supplier: APOLLO SCIENTIFIC

Description: 2,6-Dichloro-4-methylaniline

Catalog Number: (APOSOR27097-1G)

Supplier: APOLLO SCIENTIFIC

Description: 2,6-Dichloro-4-methylnicotinamide

UOM: 1 * 1 g

Catalog Number: (APOSOR309384-1G)

Supplier: APOLLO SCIENTIFIC

Description: 2,6-Dichloro-4-methylquinoline

UOM: 1 * 1 g

Supplier: APOLLO SCIENTIFIC

Description: 2',3'-Dichloro-6'-fluoroacetophenone 98%

Catalog Number: (APOSPC5827-5G)

Supplier: APOLLO SCIENTIFIC

Description: 1,2-Dichloro-4-iodoperfluorobutane

UOM: 1 * 5 g

Supplier: APOLLO SCIENTIFIC

Description: α,4-Dichloro-α-phenyltoluene

Catalog Number: (A11452.06)

Supplier: Alfa Aesar

Description: 3,5-Dichloro-2-iodotoluene ≥98%

UOM: 1 * 5 g

MSDS

Catalog Number: (BLDPBD32535-5G)

Supplier: BLD PHARMATECH GMBH

Description: Fmoc-Dap(Fmoc)-OH 95%

UOM: 1 * 5 g

Catalog Number: (ACRO345511000)

Supplier: Thermo Scientific

Description: 2',6'-Dichloro-3'-fluoroacetophenone 97%

UOM: 1 * 100 g

Supplier: Biotium

Description: Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.