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Supplier: APOLLO SCIENTIFIC
Description: 2,4-Dichloro-3-fluoroaniline

Supplier: Alfa Aesar
Description: 2,5-Dichloro-p-phenylenediamine 99%

Supplier: APOLLO SCIENTIFIC
Description: 5,7-Dichloro-2-methyl-8-quinolinol

Catalog Number: (APOSPC2487-5G)
Supplier: APOLLO SCIENTIFIC
Description: 2,4-Dichloro-3-nitrobenzotrifluoride
UOM: 1 * 5 g


Catalog Number: (BOSSBS-11784R-CY7)
Supplier: Bioss
Description: SPR, also known as sepiapterin reductase, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family. SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives. In addition, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the final reduction step of the synthesis pathway. BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine) and is required for proper dopamine synthesis. Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, a monoamine neurotransmitter deficiency without hyperphenylalaninemia. Sepiapterin reductase deficiency interferes with BH4 synthesis, resulting in DOPA-responsive dystonia and a variety of other human diseases. In addition, SPR mRNA expression is increased in the brain of Parkinson’s Disease (PD) patients, suggesting that SPR may play a role in PD.
UOM: 1 * 100 µl


Supplier: Alfa Aesar
Description: 2,6-Dichloro-4-fluorophenol ≥98%
Supplier: APOLLO SCIENTIFIC
Description: 2,6-Dichloro-3-cyanopyrazine

Catalog Number: (BOSSBS-11784R-A555)
Supplier: Bioss
Description: SPR, also known as sepiapterin reductase, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family. SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives. In addition, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the final reduction step of the synthesis pathway. BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine) and is required for proper dopamine synthesis. Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, a monoamine neurotransmitter deficiency without hyperphenylalaninemia. Sepiapterin reductase deficiency interferes with BH4 synthesis, resulting in DOPA-responsive dystonia and a variety of other human diseases. In addition, SPR mRNA expression is increased in the brain of Parkinson’s Disease (PD) patients, suggesting that SPR may play a role in PD.
UOM: 1 * 100 µl


Supplier: APOLLO SCIENTIFIC
Description: 2,4-Dichloro-6-methylpyrimidine

Supplier: Alfa Aesar
Description: Dichloro(methyl)silane ≥97%

Catalog Number: (APOSPC4084-1G)
Supplier: APOLLO SCIENTIFIC
Description: α,2-Dichloro-4-fluorotoluene 96%
UOM: 1 * 1 g


Catalog Number: (APOSOR0352-1G)
Supplier: APOLLO SCIENTIFIC
Description: 2',4'-Dichloro-6'-methylacetanilide
UOM: 1 * 1 g


Supplier: Alfa Aesar
Description: α,α'-Dichloro-o-xylene ≥98%

Supplier: APOLLO SCIENTIFIC
Description: 2,6-Dichloro-4-fluorobenzaldehyde

Catalog Number: (APOSOR14273-250MG)
Supplier: APOLLO SCIENTIFIC
Description: 2,4-Dichloro-1-(2-propynyloxy)benzene
UOM: 1 * 250 mg


Catalog Number: (APOSPC904584-1G)
Supplier: APOLLO SCIENTIFIC
Description: 3,6-Dichloro-4-fluoropyridazine
UOM: 1 * 1 g


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 88 22222.
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