You Searched For: Croton+oil

Catalog Number: (BWRLAP0084)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human eIF4B around the phosphorylation site of Serine 422.

UOM: 1 * 100 µG

Catalog Number: (BWRLAP0243)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human HSP27 around the phosphorylation site of Serine 78.

UOM: 1 * 100 µG

Catalog Number: (BWRLBS4840)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human GATA1 around the phosphorylation site of Serine 142.

UOM: 1 * 100 µG

Catalog Number: (BWRLBS4262)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human Calnexin around the phosphorylation site of Serine 583.

UOM: 1 * 100 µG

Catalog Number: (BWRLBS4791)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human GAP43 around the phosphorylation site of Serine 41.

UOM: 1 * 100 µG

Catalog Number: (BOSSBS-0801R)

Supplier: Bioss

Description: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB as well as inhibin-A/INHA-INHBA). The type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B through FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor (By similarity).

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12417R-CY7)

Supplier: Bioss

Description: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB as well as inhibin-A/INHA-INHBA). The type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B through FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor.

UOM: 1 * 100 µl

Catalog Number: (BWRLBS4195)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human isoforms Tau-4 around the phosphorylation site of Serine 356.

UOM: 1 * 100 µG

Catalog Number: (BWRLBS4196)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human isoforms Tau-4 around the phosphorylation site of Serine 396.

UOM: 1 * 100 µG

Catalog Number: (BOSSBS-12567R)

Supplier: Bioss

Description: Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.This antibody recognise the phosphorylation site of human Ser75, mouse Ser111, rat Ser112.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-5219R-HRP)

Supplier: Bioss

Description: Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

UOM: 1 * 100 µl

Catalog Number: (BWRLBS4236)

Supplier: Bioworld Technology

Description: Synthetic phosphopeptide derived from human IKKalpha/beta around the phosphorylation site of Serine 176/177.

UOM: 1 * 100 µG

Catalog Number: (BOSSBS-5151R-CY5.5)

Supplier: Bioss

Description: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.

UOM: 1 * 100 µl

Catalog Number: (USBI038886)

Supplier: US Biological

Description: Anti-NEK4 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-0540R-CY5)

Supplier: Bioss

Description: HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.

UOM: 1 * 100 µl

Catalog Number: (BWRLBS5056)

Supplier: Bioworld Technology

Description: A phospho specific peptide corresponding to residues surrounding Serine 33 and 37 and threonine 41of human Catenin-beta.

UOM: 1 * 100 µG