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Description: CAS No.: 2398-81-4
Catalog Number: ACRO147781000
UOM: 1 * 100 g
Supplier: Thermo Scientific


Description: A metabolite of nicotine in humans.
Catalog Number: APOSOR2520-25MG
UOM: 1 * 25 mg
Supplier: APOLLO SCIENTIFIC


Description: Human nicotinate phosphoribosyltransferase (NAPRTase) is localised in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
Catalog Number: PRSI90-363
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: Nicotinic acid (Niacin)
Catalog Number: 47864.
UOM: 1 * 1 items
Supplier: Merck

MSDS


Description: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.
Catalog Number: ICNA02194714.5
UOM: 1 * 500 mg
Supplier: MP Biomedicals


Description: Ethyl nicotinate for synthesis, Sigma-Aldrich®
Catalog Number: 8.06754.0250
UOM: 1 * 250 mL
Supplier: Merck


Description: Butyl nicotinate
Catalog Number: 8.00786.0100
UOM: 1 * 100 mL
Supplier: Merck


Description: Methyl nicotinate for synthesis, Sigma-Aldrich®
Catalog Number: 8.18713.0500
UOM: 1 * 500 g
Supplier: Merck


Description: Nicotinic acid (Niacin) for synthesis, Sigma-Aldrich®
Catalog Number: 8.18714.1000
UOM: 1 * 1 kg
Supplier: Merck


Description: Organic Standard, Nicotinic acid
Catalog Number: 79838-50MG
UOM: 1 * 50 mg
Supplier: Merck


Description: 6-(Ethoxycarbonyl)nicotinic acid
Catalog Number: APOSOR8507-250MG
UOM: 1 * 250 mg
Supplier: APOLLO SCIENTIFIC


Description: Organic Standard, Niacin (Nicotinic Acid)
Catalog Number: PHR1276-1G
UOM: 1 * 1 g
Supplier: Merck


Description: 2-(Phenylthio)nicotinic acid
Catalog Number: APOSOR21698-5G
UOM: 1 * 5 g
Supplier: APOLLO SCIENTIFIC


Description: 2-(Pentylthio)nicotinic acid
Catalog Number: APOSOR21407-1G
UOM: 1 * 1 g
Supplier: APOLLO SCIENTIFIC


Description: 5-(2-Chlorophenyl)nicotinic acid
Catalog Number: APOSOR470362-5G
UOM: 1 * 5 g
Supplier: APOLLO SCIENTIFIC


Description: 2-(Ethylthio)nicotinic acid
Catalog Number: APOSOR21410-5G
UOM: 1 * 5 g
Supplier: APOLLO SCIENTIFIC


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