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Supplier: Honeywell Chemicals
Description: Orthophosphoric acid 85,0-88,0, Puriss., meetSpec_BP,FCC,NF,Ph.Eur., Fluka™
Supplier: Biotium
Description: This antibody recognizes a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L( )-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.

Catalog Number: (4.80951.1000)
Supplier: MERCK PRODUCTION CHEMICALS
Description: Orthophosphoric acid 10%, EMPROVE® EXPERT Ph. Eur., NF BiopharmaceuticalProduction, SAFC®
UOM: 1 * 1 L


Supplier: Honeywell Chemicals
Description: Orthophosphoric acid 85, Puriss. p.a. Reag. Ph. Eur., ACS, ISO, Fluka™
Supplier: MERCK PRODUCTION CHEMICALS
Description: Orthophosphoric acid 85% 85, EMPROVE® ESSENTIAL JPE, BP, E338, Ph. Eur., NF, extra_pure suitable for use as excipient, SAFC®

Catalog Number: (PRSI29-710)
Supplier: ProSci Inc.
Description: ACP1 belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate.The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene.
UOM: 1 * 100 µG


Catalog Number: (PRSI30-580)
Supplier: ProSci Inc.
Description: Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases.Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
UOM: 1 * 50 µG


Catalog Number: (PRSI26-034)
Supplier: ProSci Inc.
Description: ACP2 is the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Lysosomal acid phosphatase is comprised of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 50 µG


Catalog Number: (PRSI34-028)
Supplier: ProSci Inc.
Description: Prostate specific acid phosphatase (PSAP) is an enzyme that catalyses the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesised under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
UOM: 1 * 100 µG

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Catalog Number: (PRSI33-682)
Supplier: ProSci Inc.
Description: Prostate specific acid phosphatase (PSAP) is an enzyme that catalyses the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesised under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
UOM: 1 * 100 µG

New Product


Catalog Number: (PRSI33-455)
Supplier: ProSci Inc.
Description: It recognises a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyses the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesised as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
UOM: 1 * 100 µG

New Product


Catalog Number: (47863.)
Supplier: Merck
Description: L(+)-Ascorbic acid
UOM: 1 * 1 items

Catalog Number: (21639-5ML)
Supplier: Merck
Description: Caprylic acid, Supelco®
UOM: 1 * 5 mL


Catalog Number: (19667-5G)
Supplier: Merck
Description: 1-Butylboronic acid, Supelco®
UOM: 1 * 5 g


Supplier: Merck
Description: 3-Oxoglutaric acid for synthesis, Sigma-Aldrich®

Supplier: Merck
Description: Pyruvic acid for synthesis, Sigma-Aldrich®

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