You Searched For: Pentafluorophenyl+nicotinate

Catalog Number: (PRSI27-667)

Supplier: ProSci Inc.

Description: PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

UOM: 1 * 100 µG

Catalog Number: (PRSI27-668)

Supplier: ProSci Inc.

Description: PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

UOM: 1 * 50 µG

Supplier: MP Biomedicals

Description: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.

Catalog Number: (GSK5294-1G)

Supplier: Merck

Description: NICOTINE DITARTRATE (NICOTINE BITARTRATE 1 * 1 g

UOM: 1 * 1 g

Catalog Number: (36733-250MG)

Supplier: Merck

Description: (-)-NICOTINE 1 * 250 l

UOM: 1 * 250 mg

Catalog Number: (GSK06347-100MG)

Supplier: Merck

Description: NICOTINE BASE 1 * 100 mg

UOM: 1 * 100 mg

Catalog Number: (GSK6347-100MG)

Supplier: Merck

Description: NICOTINE BASE 1 * 100 mg

UOM: 1 * 100 mg

Catalog Number: (PHR2533-50MG)

Supplier: Merck

Description: NICOTINE RELATED COMPOUND C 1 * 50 mg

UOM: 1 * 50 mg

Catalog Number: (GSK5301-100MG)

Supplier: Merck

Description: (1',2'S)-NICOTINE-1'-N-OXIDE 1 * 100 mg

UOM: 1 * 100 mg

Catalog Number: (PHR2532-500MG)

Supplier: Merck

Description: NICOTINE BITARTRATE DIHYDRATE 1 * 500 mg

UOM: 1 * 500 mg

Catalog Number: (PHR3060-50MG)

Supplier: Merck

Description: Nicotine Related Compound A/EP Impurity A pharmaceutical secondary standard, certified reference material 1 * 50 mg

UOM: 1 * 50 mg

Catalog Number: (8.41333.0100)

Supplier: Merck

Description: Nicotinic Acid N-Oxide For Synthesis 1 * 100 g

UOM: 1 * 100 g

Catalog Number: (PHR3064-50MG)

Supplier: Merck

Description: Nicotine Related Compound G pharmaceutical secondary standard, certified reference material 1 * 50 mg

UOM: 1 * 50 mg

Catalog Number: (PHR3061-50MG)

Supplier: Merck

Description: Nicotine Related Compound B pharmaceutical secondary standard, certified reference material 1 * 50 mg

UOM: 1 * 50 mg

Catalog Number: (PHR3062-50MG)

Supplier: Merck

Description: Nicotine Related Compound D certified reference material, pharmaceutical secondary standard 1 * 50 mg

UOM: 1 * 50 mg

Catalog Number: (PHR3063-50MG)

Supplier: Merck

Description: Nicotine Related Compound F pharmaceutical secondary standard, certified reference material 1 * 50 mg

UOM: 1 * 50 mg