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Image Unavailable-APOSBIP1010-1MG

Phorbol ≥99%

Supplier: APOLLO SCIENTIFIC
Description: Unsubstituted parent diterpene from which phorbol esters are derived; biologically inactive in most assays

Image Unavailable-APOSBIP1016-5MG

Phorbol-12,13-dibutyrate ≥99%

Supplier: APOLLO SCIENTIFIC
Description: Widely used PKC activator; less potent than PMA, but also less hydrophobic, making it easier to wash out of cells in tissue culture.

Product Image-ACRO356150010

Phorbol-12-myristate-13-acetate 97%

Supplier: Thermo Scientific
Description: CAS No.: 16561-29-8

Image Unavailable-APOSBIP1020-5MG

Phorbol-12-myristate-13-acetate ≥99.5%

Supplier: APOLLO SCIENTIFIC
Description: This is the most commonly used phorbol ester.  It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues, and is a very potent mouse skin tumor promoter. Crit. Rev. Toxicol. 8:  153-197 (1980)

Image Unavailable-TNB-4975-UL100

Cell Stimulation Cocktail

Catalog Number: (TNB-4975-UL100)
Supplier: Tonbo Biosciences
Description: Cell stimulation cocktail is a ready to use cocktail that can be used for polyclonal cell activation. It is composed of the phorbol ester, PMA (phorbol 12-Myristate 13-Acetate), a calcium ionophore (Ionomycin), and the protein transport inhibitors Brefeldin A and Monensin. It can be used to elicit cytokine production and retention in a variety of cell types allowing for detection of intracellular protein by flow cytometry.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1477R-HRP

Anti-ARFIP1 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Catalog Number: (BOSSBS-1477R-HRP)
Supplier: Bioss
Description: Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1477R-CY5

Anti-ARFIP1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1477R-CY5)
Supplier: Bioss
Description: Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6425R-CY5.5

Anti-TRP12 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-6425R-CY5.5)
Supplier: Bioss
Description: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6425R-CY7

Anti-TRP12 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6425R-CY7)
Supplier: Bioss
Description: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6425R-CY5

Anti-TRP12 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6425R-CY5)
Supplier: Bioss
Description: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6425R-A488

Anti-TRP12 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-6425R-A488)
Supplier: Bioss
Description: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1477R-A555

Anti-ARFIP1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1477R-A555)
Supplier: Bioss
Description: Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1477R-CY7

Anti-ARFIP1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1477R-CY7)
Supplier: Bioss
Description: Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1477R-A750

Anti-ARFIP1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1477R-A750)
Supplier: Bioss
Description: Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1477R-A350

Anti-ARFIP1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-1477R-A350)
Supplier: Bioss
Description: Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6425R-HRP

Anti-TRP12 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6425R-HRP)
Supplier: Bioss
Description: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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