You Searched For: Poly(vinyl+chloride),+carboxylated

Catalog Number: (BRDY223663)

Supplier: Brady

Description: These floor marking labels are made of durable vinyl and are provided with a non-slip laminate layer. They are used to warn people for potential hazards.

UOM: 1 * 1 items

Catalog Number: (46796.A1)

Supplier: Alfa Aesar

Description: Diaion® SA10A(Cl) is an ion exchange resin, cross-linked, strongly basic gel type I, 1.3 meq/ml on PS-DVB.

UOM: 1 * 1 kg

Catalog Number: (BOSSBS-13018R-A555)

Supplier: Bioss

Description: DNA polymerase activity is essential for replication, repair, recombination and mutagenesis. DNA polymerases can often bypass DNA lesions that block DNA replication, thereby allowing the replication of damaged DNA. One such DNA polymerase is the distributive enzyme DNA Pol i, which is encoded by the POLI gene. POLI is located on human chromosome 18q21.2, a region often implicated in the etiology of many human cancers. At thymine templates, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, adenosine. DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions. DNA Pol i acts sequentially with DNA Pol Ω, which is essential for damage-induced mutagenesis, to complete the DNA lesion bypass. Therefore, replication involving DNA Pol i is likely to be highly mutagenic.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-13018R-FITC)

Supplier: Bioss

Description: DNA polymerase activity is essential for replication, repair, recombination and mutagenesis. DNA polymerases can often bypass DNA lesions that block DNA replication, thereby allowing the replication of damaged DNA. One such DNA polymerase is the distributive enzyme DNA Pol i, which is encoded by the POLI gene. POLI is located on human chromosome 18q21.2, a region often implicated in the etiology of many human cancers. At thymine templates, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, adenosine. DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions. DNA Pol i acts sequentially with DNA Pol Ω, which is essential for damage-induced mutagenesis, to complete the DNA lesion bypass. Therefore, replication involving DNA Pol i is likely to be highly mutagenic.

UOM: 1 * 100 µl

Catalog Number: (APOSOR451801-25G)

Supplier: APOLLO SCIENTIFIC

Description: (±)-3-Buten-2-ol

UOM: 1 * 25 g

Supplier: Alfa Aesar

Description: Polyethyleneimine, M.W. 10,000 ≥99%, branched

Catalog Number: (BOSSBS-9435R-CY5.5)

Supplier: Bioss

Description: Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly(A) site that leads to synthesis of the poly(A) tail at the 3-prime end of the upstream cleavage product. The poly(A) polymerase (PAP) is required The adenosine addition reaction depends on poly(A) polymerase (PAP) activity. The testis express PAP-beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-beta plays a critical role in male germ cell production. PAP-beta-deficient transgenic mice display impaired expression of haploid-specific genes that are necessary for spermatogenesis. The intronless gene encoding human PAP-beta maps to chromosome 7p22.3.

UOM: 1 * 100 µl

Supplier: Brady

Description: Specialised aggressive adhesive allows sticking, removing, and repositioning labels with ease without leaving behind adhesive residue or surface damage.

Catalog Number: (BRDY131575)

Supplier: Brady

Description: These self-laminating vinyl labels are ideal for labelling highly curved surfaces, wires and cables. The labels feature a white printable area with clear 'tail' that wraps around marker that serves as over-laminate to protect the text, providing superior resistance to abrasion, dirt, oils, solvents, water and excessive handling.

UOM: 1 * 1 Roll

Supplier: Kango

Description: Stools with high density comfortable foam and vinyl coating.

Catalog Number: (PRSI36-169)

Supplier: ProSci Inc.

Description: Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair and is associated with the negatively charged polymer of adenosine 5'-diphosphate (ADP)-ribose (PAR). PAR is synthesized from nicotinamide adenine dinucleotide (NAD+) by the poly(ADP-ribose) polymerase protein family (PARPs), of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks. PARP-1 is selectively activated by DNA strand breaks to catalyze the addition of long branched chains of PAR to a variety of nuclear proteins, most notably PARP itself. The amount of PAR formed in living cells with DNA damage is commensurate with the extent of the damage. Under DNA damage conditions, PAR undergoes a rapid turnover, with a half-life in the range of minutes, as PAR is rapidly hydrolyzed and converted to free ADP-ribose by the enzyme poly(ADP-ribose)glycohydrolase (PARG). PAR regulates not only cell survival and cell-death programmes, but also an increasing number of other biological functions with which novel members of the PARP family have been associated. These include transcriptional regulation, cell division, intracellular trafficking, inflammation and energy metabolism.

UOM: 1 * 100 µG

Supplier: Thermo Scientific

Description: Vinyltriethoxysilane 97%

Supplier: APOLLO SCIENTIFIC

Description: 60 wt % dispersion in water; 0.05-0.5 micron particles.

Catalog Number: (ACRO115660100)

Supplier: Thermo Scientific

Description: 4,4'-Dimethoxystilbene 99%

UOM: 1 * 10 g

Catalog Number: (BOSSBS-9104R-CY5)

Supplier: Bioss

Description: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.

UOM: 1 * 100 µl

Catalog Number: (59005.)

Supplier: Biotium

Description: Ready-to-use solution of Pluronic® F-127, a nonionic detergent useful for solubilizing hydrophobic dye molecules such as AM esters of Fura-2, Fluo-3, Indo-1, or Rhod-2 to facilitate cell loading.

UOM: 1 * 30 mL