You Searched For: (R)-tert-Butyl+(2-oxoazepan-3-yl)carbamate

Description: KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.

Catalog Number: BOSSBS-5403R

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterised by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Catalog Number: BOSSBS-12176R-A750

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Anti-alpha 1 Sodium Potassium ATPase Rabbit Polyclonal Antibody

Catalog Number: ABCAAB217947-100

UOM: 1 * 100 µl

Supplier: Abcam

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Description: Anti-Sodium Potassium ATPase Mouse Monoclonal Antibody [clone: EP1845Y]

Catalog Number: ABCAAB283318-100

UOM: 1 * 100 µl

Supplier: Abcam

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Description: Anti-Sodium Potassium ATPase Rabbit Monoclonal Antibody [clone: EP1845Y] (Alexa Fluor® 488)

Catalog Number: ABCAAB197713-100

UOM: 1 * 100 µl

Supplier: Abcam

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Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).

Catalog Number: BOSSBS-6468R-A647

UOM: 1 * 100 µl

Supplier: Bioss

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Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Catalog Number: BOSSBS-6672R-A555

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Catalog Number: BOSSBS-2960R-CY5.5

UOM: 1 * 100 µl

Supplier: Bioss

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Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterised by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).

Catalog Number: BOSSBS-6468R-A680

UOM: 1 * 100 µl

Supplier: Bioss

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Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Catalog Number: BOSSBS-6672R-HRP

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Anti-alpha 1 Sodium Potassium ATPase Mouse Monoclonal Antibody [clone: 464,6] (Alexa Fluor® 488)

Catalog Number: ABCAAB197496-100

UOM: 1 * 100 µl

Supplier: Abcam

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Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.

Catalog Number: BOSSBS-7689R-A350

UOM: 1 * 100 µl

Supplier: Bioss

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Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Catalog Number: BOSSBS-3034R-A555

UOM: 1 * 100 µl

Supplier: Bioss

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Description: This is the catalytic component of the active enzyme, which catalyses the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Catalog Number: BOSSBS-3034R-A680

UOM: 1 * 100 µl

Supplier: Bioss

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Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Catalog Number: BOSSBS-3034R-A647

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Neuronal and cardiac cells are excited by voltage-gated ion channels. Voltage-gated K+ channels in the plasma membrane control the repolarisation and the frequency of action potentials in neurons, muscles and other excitable cells. Mutations interfering with potassium ion channels are known to cause a variety of disorders. KCNG2 (potassium voltage-gated channel subfamily G member 2) is also known as voltage-gated potassium channel subunit KV6.2, cardiac potassium channel subunit or KCNF2 and is a 466 amino acid protein. KCNG2 is a multi-pass membrane protein abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and detected at lower concentrations in brain, lung and placenta. KCNG2 is an electrically silent subunit that forms heterodimers with KV2.1, creating a unique functional K+ channel. KCNG2-KV2.1 heterodimers are known to be inhibited by tetraethylammonium and propafenone. KCNG2 is thought to downregulate potassium channel currents because KCNG2-KV2.1 heterodimers generate smaller currents than KV2.1 homodimers.

Catalog Number: BOSSBS-9857R-A750

UOM: 1 * 100 µl

Supplier: Bioss

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