You Searched For: SIMS+PORTEX

Catalog Number: (PRSI28-566)

Supplier: ProSci Inc.

Description: ARNTL is a general dimerization partner for a subset of the basic-helix-loop-helix (bHLH)-PER-ARNT-SIM (PAS) superfamily of transcriptional regulators.

UOM: 1 * 100 µG

Catalog Number: (BINH1005806)

Supplier: Binhold, Paul Lehrmittel

Description: Ideal for training. This revolutionary training arm provides complete venous access for IV therapy and phlebotomy, plus sites for intramuscular and intradermal injections.

UOM: 1 * 1 items

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Catalog Number: (PRSI33-139)

Supplier: ProSci Inc.

Description: HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (alpha and beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stable under both conditions. Besides their critical role in hypoxic response, HIFs regulates the transcription of genes responsible for angiogenesis, erythropoiesis/iron-metabolism, glucose metabolism, cell proliferation/survival, adipogenesis, carotid body formation, B lymphocyte development and immune reactions.

UOM: 1 * 100 µG

New Product

Supplier: Sartorius Balances

Description: Semi-micro balances have a readability of 0,01 mg or 10 µg and a maximum weighing capacity of up to 220 g.

Catalog Number: (548-9024)

Supplier: VWR Collection

Description: VWR®, Chromatography vial, 40,00 ml, Non sterile, Cap included: Yes, Cap material: PP

UOM: 1 * 2.000 items

Supplier: Sartorius Balances

Description: Cubis® II MCA high-capacity toploading balances with advanced user interface offer a maximum load between 11,2 and 70,2 kg and readability between 0,1 and 1 g provide the ideal model for every application.

Supplier: Sartorius Balances

Description: Quintix® Pro laboratory balances are not just about meeting your expectations but exceeding them. The balances have an array of premium features that enhance usability, flexibility, and incorporate an eco-friendly design.

Supplier: Hichrom Limited

Description: Stainless steel, Empty columns: Yes, Ø int.: 7,50 mm, Length: 75 mm

Supplier: Sartorius Balances

Description: The Cubis® II laboratory balances are modular, providing choice between applications and configurations that best suit the users' needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions. The Cubis® II range of high-capacity micro balances with a maximum load between 32 and 111 g and a readability between 0,001 mg and 0,002 mg provide the ideal choice for a broad range of applications.

Supplier: Sartorius Balances

Description: Cubis® II MCA analytical balances with advanced user interface offer maximum weighing capacity between 120 and 520 g in combination with readability of 0.1 mg.

Supplier: Hichrom Limited

Description: Stainless steel, Empty columns: Yes, Ø int.: 4,00 mm, Length: 50 mm

Supplier: Thermo Scientific

Description: PS, untreated, pinchbar design. 96-MicroWell™ plates for fluorescence and luminescence based assays. Black plates for fluorescence reading with minimum back-scattered light and background fluorescence. White plates for luminescence with maximum reflection and minimal autoluminescence.

Catalog Number: (734-1178)

Supplier: Thermo Scientific

Description: PS, ready to use plates pre-coated with poly-D-lysine, with lid.

UOM: 1 * 20 items

Supplier: Sartorius Balances

Description: Cubis® II MCE analytical balances with essential user interface offer a maximum weighing capacity between 120 and 520 g in combination with readability of 0.1 mg.

Supplier: Sartorius Balances

Description: Cubis® II MCA micro balances with advanced user interface offer readability of 1 μg and a maximum capacity between 3,1 and 10,1 g. Used to determine the exact weight of very small sample quantities.

Supplier: Sartorius Balances

Description: Cubis® II MCE high-capacity toploading balances with essential user interface offer a maximum load between 11,2 and 70,2 kg and readability between 0,1 and 1 g provide the ideal model for every application.