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Catalog Number: (PRSI91-073)
Supplier: ProSci Inc.
Description: Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
UOM: 1 * 50 µG


Supplier: Retsch GmbH
Description: Ultrasonic bath accessories, Basket, stainless steel

Supplier: Shenandoah Biotechnology
Description: Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.

Catalog Number: (BAND8228)
Supplier: BANDELIN-ELECTRONIC
Description: Ultrasonic bath accessories, Stainless steel lid MD 70
UOM: 1 * 1 items

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Catalog Number: (BAND3512)
Supplier: BANDELIN-ELECTRONIC
Description: Ultrasonic bath accessories, Beaker holder, PH 255-11
UOM: 1 * 1 items


Supplier: BANDELIN-ELECTRONIC
Description: STAMMOPUR 24 is formulated for cleaning and disinfection of respirators, protective equipment, medical tnstruments and laboratory equipment. The product was especially developed for cleaning and disinfection in an ultrasonic bath and allows short sonication times at low dosage.

Catalog Number: (PRSI92-281)
Supplier: ProSci Inc.
Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesised as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.
UOM: 1 * 50 µG


Supplier: GRANT INSTRUMENTS
Description: Ultrasonic bath accessories, Replacement lid, XAL5

Supplier: BRANSON
Description: Ultrasonic bath accessories, Bransonic®, Tank cover, plastic

Supplier: Merck Millipore (Calbiochem‎)
Description: Cyclopamine, <i>V. californicum</i>, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonises sonic hedgehog signaling through direct interaction with Smo.

Supplier: BRANSON
Description: Ultrasonic bath accessories, Spare lid, plastic

Supplier: BANDELIN-ELECTRONIC
Description: Ultrasonic bath accessories, Lid, stainless steel

Supplier: GRANT INSTRUMENTS
Description: Ultrasonic bath accessories, Replacement lid, XAL3

Supplier: HEATHROW
Description: These reagent reservoir chillers are the ice-free, non-toxic way to extend the working period and preserve integrity for temperature sensitive reagents. They are made from sonic welded, engineered PP that ensures a leak free design.

Supplier: HAVERBOECKER
Description: It is used for thorough and gentle cleaning of sieves.

Supplier: ELMA SCHMIDBAUER
Description: The Elmasonic EASY series focuses on test sieve cleaning, HPLC solvent degassing and other laboratory applications, such as dissolving substances that are only poorly soluble, producing emulsions and accelerating reactions. Users can choose between different programs, such as 'sieve cleaning', 'degas' or 'sample preparation', to activate the correct ultrasonic parameters. These enable all process to be easily standardised and repeated, which makes achieving reproducible results and laboratory work significantly easier.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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