You Searched For: Security+Locks

Catalog Number: (BOSSBS-5898R-A750)

Supplier: Bioss

Description: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea (By similarity).

UOM: 1 * 100 µl

Supplier: Lenz Laborglas GmbH & CO.KG

Description: DURAN®, borosilicate glass, PTFE blade and securing screw. Gas tight closure for vacuum stirring apparatus up to 10⁻³ mbar at continuous operational speed of 800 min⁻¹.

Catalog Number: (BOSSBS-5898R-A488)

Supplier: Bioss

Description: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea (By similarity).

UOM: 1 * 100 µl

Supplier: Liebherr

Description: These are heavy duty MediLine models with forced air cooling. The controller features door and temperature alarms which can be customised to suit the end user. Controller can be locked. The refrigerant used is hydrocarbon. Units have 83 to 60 mm insulation and 2 castors with brakes.

Supplier: Thermo Fisher Scientific

Description: ClipTip filtered pipette tips provide security with a unique and innovative interlocking technology that ensures a complete seal on every channel with minimal tip attachment and ejection force.

Supplier: THERMO BIOPROCESS DIVISION

Description: BioProcess Container™ (BPC™) systems include two-dimensional single-use bags for liquid handling. Manufactured from medical-grade plastics (cGMP compliant) and configured with ports, tubing and fittings, BPC™ systems provide an efficient means for sterile liquid handling in research and production settings.

Catalog Number: (BOHLM564-01)

Supplier: Bohlender

Description: Expandable cable conduit to bundle several hoses or signal cables, can be cut to the required length.

UOM: 1 * 1 items

Catalog Number: (STUA10098-17)

Supplier: Cole Parmer

Description: Spare securing bar, stuart®, For: SI500

UOM: 1 * 1 items

Supplier: HENKE SASS WOLF

Description: Disposable, two-piece, without needle, PP barrel and PE piston, latex- and silicone oil-free. Syringes are also available with especially designed oral tip, which prevents accidental Luer or hypodermic connection, in volumes of 5 or 10 ml. Incompatible with injection needles. Please enquire for details.

Catalog Number: (129-3980)

Supplier: RUBBERMAID

Description: Groundskeeper® Tuscan security kit, Groundskeeper®

UOM: 1 * 1 items

Catalog Number: (720-2576)

Supplier: B. Braun

Description: These stoppers ensure a sterile closure of female connections after use.

UOM: 1 * 100 items

Catalog Number: (BOSSBS-5898R-FITC)

Supplier: Bioss

Description: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea (By similarity).

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-5898R-CY5)

Supplier: Bioss

Description: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea (By similarity).

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-5898R-A555)

Supplier: Bioss

Description: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea (By similarity).

UOM: 1 * 100 µl

Supplier: VELP SCIENTIFIC

Description: Safe and compact digital multi-position magnetic hotplate stirrers available with 6 or 15 positions. The MULTI-HS include features such as timer, safety lock, the brushless motor provides maximum performance and safety.

Catalog Number: (BOSSBS-2923R)

Supplier: Bioss

Description: Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.

UOM: 1 * 100 µl