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Catalog Number: (BOSSBS-1834R-CY7)
Supplier: Bioss
Description: IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-10069R)
Supplier: Bioss
Description: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-10069R-CY3)
Supplier: Bioss
Description: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-10069R-A647)
Supplier: Bioss
Description: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-8193R-CY5.5)
Supplier: Bioss
Description: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6321R-CY7)
Supplier: Bioss
Description: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-8324R-CY5)
Supplier: Bioss
Description: Headpin is a skin-specific, UV-repressible serine proteinase inhibitor (serpin) belonging to the ovalbumin serpin family. Headpin is abundant in the human keratinocyte cell line HaCaT, and in lesional keratinocytes from psoriatic skin. Headpin downregulation occurs in squamous cell carcinoma of the oral cavity and in squamous cell carcinoma cell lines of the head and neck.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1253R-CY3)
Supplier: Bioss
Description: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1253R-A647)
Supplier: Bioss
Description: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1253R-FITC)
Supplier: Bioss
Description: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12309R-HRP)
Supplier: Bioss
Description: HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. There are multiple transcripts of the Hoxb3 gene, and the anterior boundaries of its expression vary at different stages of development. Hoxb3 plays a role in the proliferation and differentiation of both early myeloid and lymphoid developmental pathways. Hoxb3 also has overlapping function in mediating the migration of pharyngeal organ primordia and is expressed in very restricted domains in the future hindbrain. Hoxb6 controls the generation, proliferation and survival of erythroid progenitor cells. The Hoxb6 protein is expressed in the suprabasal layer of the early developing epidermis and throughout the upper layers of late fetal and adult human skin. Hoxb6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. Hoxb6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. Hoxb6 genes are also expressed in normal adult lung.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-8460R-CY7)
Supplier: Bioss
Description: FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G∫ and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Catalog Number: (SCAA960501)
Supplier: Essity
Description: Get an easy start into great hand hygiene with Tork starter pack with Tork mildly scented foam soap. Combines one white S4 skincare dispenser and one mild foam soap refill.
UOM: 1 * 6 items

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Catalog Number: (BOSSBS-5863R-CY7)
Supplier: Bioss
Description: Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-8193R-A680)
Supplier: Bioss
Description: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-8460R-CY5.5)
Supplier: Bioss
Description: FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G∫ and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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