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Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognised as specific for DNA; it was the first DNase to be crystallised; and it was the first DNase for which a specific protein inhibitor was characterised. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesised in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
Catalog Number: BOSSBS-7651R-A750
UOM: 1 * 100 µl
Supplier: Bioss


Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
Catalog Number: BOSSBS-7651R-A647
UOM: 1 * 100 µl
Supplier: Bioss


Description: Chloroform : Isoamyl alcohol (24:1) (v/v) for molecular biology DNase-, RNase-, protease-free
Catalog Number: ACRO327155000
UOM: 1 * 500 mL
Supplier: Thermo Scientific

MSDS


Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognised as specific for DNA; it was the first DNase to be crystallised; and it was the first DNase for which a specific protein inhibitor was characterised. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesised in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
Catalog Number: BOSSBS-7651R-A680
UOM: 1 * 100 µl
Supplier: Bioss


Description: Deoxyribonuclease I (usually called DNase I), is an endonuclease coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. It acts on single-stranded DNA, double-stranded DNA, and chromatin.
Catalog Number: ROCKMB-101-0500
UOM: 1 * 0,5 KU
Supplier: Rockland Immunochemicals


Description: X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside) 99+% for molecular biology DNase-, RNase-, protease-free
Catalog Number: ACRO327245000
UOM: 1 * 500 mg
Supplier: Thermo Scientific


Description: For various microbiological applications.
Catalog Number: 295025ZA
UOM: 1 * 20 items
Supplier: VWR Chemicals

Description: CAS No.: 38641-82-6
Catalog Number: ACRO327345000
UOM: 1 * 500 mL
Supplier: Thermo Scientific


Description: For protein solubilization and denaturation. DNase-, RNase-, protease-, and cyanate-free.
Catalog Number: 4111-F9
UOM: 1 * 50 kg
Supplier: Avantor

MSDS


Description: N,N-Dimethylformamide 99.8% for molecular biology DNase-, RNase-, protease-free
Catalog Number: ACRO327175000
UOM: 1 * 500 mL
Supplier: Thermo Scientific


Description: The peqGOLD DNase I Digest Kit is optimised for use with peqGOLD RNA extraction protocols. Normally DNase I digestion is not required for RNA purified with peqGOLD RNA Mini Columns as our silica-based spin column technology efficiently removes the majority of DNA without enzymatic digestion. However, certain sensitive RNA applications may require further DNA removal.
Catalog Number: 13-1091-01
UOM: 1 * 50 Tests
Supplier: VWR Chemicals

MSDS


Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
Catalog Number: BOSSBS-7651R
UOM: 1 * 100 µl
Supplier: Bioss


Description: EDTA tetrasodium salt tetrahydrate 99.5% for molecular biology DNase-, RNase-, protease-free
Catalog Number: ACRO327211000
UOM: 1 * 100 g
Supplier: Thermo Scientific

MSDS


Description: Proteinase K is used to destruct proteins in cell lysates (tissue, cultured cells) and to liberate nucleic acids, since it very effectively digests DNases and RNases.
Catalog Number: A4392.0001
UOM: 1 * 1 mL
Supplier: PanReac AppliChem

MSDS


Description: Ammonium peroxodisulphate (APS) 99+% for molecular biology DNase-, RNase-, protease-free
Catalog Number: ACRO327085000
UOM: 1 * 500 g
Supplier: Thermo Scientific


Description: Tested for absence of detectable aldehydes and ammeline. DNase-, RNase-, and protease-free.
Catalog Number: 7716-87
UOM: 1 * 10 kg
Supplier: MACRON AVANTOR BRAND


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