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Catalog Number: (BOSSBS-7852R-A680)
Supplier: Bioss
Description: ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7967R)
Supplier: Bioss
Description: APOL3 may be involved in cytoplasmic lipid transport or allow the binding of lipids to organelles. It is widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and testis. There are three named isoforms.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11126R)
Supplier: Bioss
Description: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus. Has some neurite outgrowth-promoting activity.
UOM: 1 * 100 µl


Catalog Number: (BSENR-154-100)
Supplier: Biosensis
Description: Arc (also termed activity-regulated cytoskeleton-associated protein or Arg3.1), is an effector immediate early gene whose upregulation has been demonstrated during events of synaptic plasticity. Arg3.1 expression is detectable in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus, hypothalamus, amygdala.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12128R-A680)
Supplier: Bioss
Description: Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localisation to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7 and 3.7 kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11330R)
Supplier: Bioss
Description: There are three sorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain. Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues. Human SorCS1 is detected in fetal and infant brain and in fetal retina. Alternative splicing of murine SorCS1 also results in four isoforms. Murine isoform 1 is highly expressed in brain and at lower levels in heart, liver and kidney. It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex. Murine isoform 2 is highly expressed in liver and at lower levels in heart, brain, kidney and testis.
UOM: 1 * 100 µl


Supplier: Avantor
Description: Single element plasma standards are used for accuracy and easy of calibration, along with precise detection of trace impurities.

Catalog Number: (BOSSBS-6755R-A555)
Supplier: Bioss
Description: Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
UOM: 1 * 100 µl


Catalog Number: (TEST0560.8353)
Supplier: TESTO
Description: This non contact thermometer measures surface temperature, moisture and dew point. It therefore helps to detect mold in buildings.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-7671R-A350)
Supplier: Bioss
Description: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1291R)
Supplier: Bioss
Description: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].
UOM: 1 * 100 µl


Supplier: Biotium
Description: This antibody reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.

Catalog Number: (BOSSBS-11126R-HRP)
Supplier: Bioss
Description: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus. Has some neurite outgrowth-promoting activity.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11126R-A750)
Supplier: Bioss
Description: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus. Has some neurite outgrowth-promoting activity.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-2101R-CY5.5)
Supplier: Bioss
Description: The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6755R-A750)
Supplier: Bioss
Description: Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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