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Catalog Number: (BOSSBS-13553R)

Supplier: Bioss

Description: Anti-ZBED3 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12287R)

Supplier: Bioss

Description: Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules; and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12296R)

Supplier: Bioss

Description: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-13264R)

Supplier: Bioss

Description: Anti-GADL1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12299R)

Supplier: Bioss

Description: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-12280R)

Supplier: Bioss

Description: Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis (By similarity).

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-13263R)

Supplier: Bioss

Description: Anti-GAD1/GAD2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-4192R)

Supplier: Bioss

Description: SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-2802R)

Supplier: Bioss

Description: Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-2809R)

Supplier: Bioss

Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-7550R)

Supplier: Bioss

Description: Ancient ubiquitous protein 1 (AUP1) contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. It has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-6468R)

Supplier: Bioss

Description: Anti-KCNJ8 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-0901R)

Supplier: Bioss

Description: Anti-RPSA Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-6463R)

Supplier: Bioss

Description: Anti-CASP8 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-6359R)

Supplier: Bioss

Description: Anti-PPAT Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-6293R)

Supplier: Bioss

Description: Anti-ACP1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl