You Searched For: PROSCI

Catalog Number: (PRSI92-597)

Supplier: ProSci Inc.

Description: Transforming growth factor- beta (TGF- beta ) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF- beta regulates cellular processes by binding to three high-affinity cell surface receptors: TGF- beta receptor type I (TGF- beta -RI), TGF- beta receptor type II (TGF- beta -RII), and TGF- beta beta receptor type III (TGF- beta -RIII). TGF- beta RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF- beta ) receptor subfamily. TGF- beta RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

UOM: 1 * 50 µG

Catalog Number: (PRSI61-113)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI42-051)

Supplier: ProSci Inc.

Description: Anti-BAG6 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (PRSI96-625)

Supplier: ProSci Inc.

Description: Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

UOM: 1 * 20 µG

Catalog Number: (PRSI28-197)

Supplier: ProSci Inc.

Description: The gene encoding the hypothetical protein HS747E2A is located on chromosome 22.

UOM: 1 * 100 µG

Catalog Number: (PRSI23-505)

Supplier: ProSci Inc.

Description: Anti-MRAS Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

New Product

Catalog Number: (PRSI33-434)

Supplier: ProSci Inc.

Description: Recognises a protein of 40 kDa, identified as cytokeratin-19 (CK19), which is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI79-547)

Supplier: ProSci Inc.

Description: Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.

UOM: 1 * 100 µG

Catalog Number: (PRSIXW-8138)

Supplier: ProSci Inc.

Description: FUNCTION: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
SIMILARITY: Belongs to the SLC12A transporter family.
SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in many tissues.

UOM: 1 * 50 µG

Catalog Number: (PRSI32-127)

Supplier: ProSci Inc.

Description: CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

UOM: 1 * 100 µG

Catalog Number: (PRSI35-391)

Supplier: ProSci Inc.

Description: Anti-T. gondii Goat Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 1 mL

Catalog Number: (PRSI4307P)

Supplier: ProSci Inc.

Description: STEAP2 peptide is used for blocking the activity of STEAP2 antibody.

UOM: 1 * 50 µG

Catalog Number: (PRSI30-181)

Supplier: ProSci Inc.

Description: MRTO4 is a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly.This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly.

UOM: 1 * 100 µG

Catalog Number: (PRSI91-692)

Supplier: ProSci Inc.

Description: Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endothelium. COL8A1 forms homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 contains one C1q domain and is primarily expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury, in atherosclerosis and in diabetes. COL8A1 may have a role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

UOM: 1 * 50 µG

Catalog Number: (PRSIXP-5286BT)

Supplier: ProSci Inc.

Description: Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.

UOM: 1 * 50 µG

Catalog Number: (PRSI46-161)

Supplier: ProSci Inc.

Description: Anti-PEBP1 Goat Polyclonal Antibody

UOM: 1 * 100 µG