You Searched For: PROSCI

Catalog Number: (PRSI29-471)

Supplier: ProSci Inc.

Description: BXDC5 may be required for ribosome biogenesis.

UOM: 1 * 50 µG

Catalog Number: (PRSI28-988)

Supplier: ProSci Inc.

Description: HMG-box containing protein 1 (HBP1) is a member of the high mobility group (HMG) of chromosomal proteins. It is a sequence-specific HMG transcription factor. Several features of HBP1 suggest an intriguing role as a transcriptional and cell cycle regulator in differentiated cells and it may represent a unique transcriptional repressor with a role in initiation and establishment of cell cycle arrest during differentiation.

UOM: 1 * 50 µG

Catalog Number: (PRSI4377P)

Supplier: ProSci Inc.

Description: Nhe-1 peptide is used for blocking the activity of Nhe-1 antibody.

UOM: 1 * 50 µG

Catalog Number: (PRSI33-658)

Supplier: ProSci Inc.

Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterised by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI4997)

Supplier: ProSci Inc.

Description: OCC-1 Antibody: OCC-1 (Overexpressed in colon carcinoma-1) was initially identified as a novel human cDNA overexpressed in a colon carcinoma cell line. Elevated levels of OCC-1 mRNA were observed in three of eight colon carcinomas, suggesting that OCC-1 may be a hallmark of only a subset of colon carcinomas. It is highly expressed in skeletal muscle, kidney, placenta, and pancreas tissues, with low to no expression in heart, brain, lung and liver tissues. At least two different OCC-1 mRNA species are known to exist.

UOM: 1 * 100 µG

Catalog Number: (PRSI51-140)

Supplier: ProSci Inc.

Description: Anti-IL7R Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

Catalog Number: (PRSI27-800)

Supplier: ProSci Inc.

Description: ZNF395 is a novel transcription factor shuttling between nucleus and cytoplasm and bind to the specific GCCGGCG, which is an essential cis-element for HD gene expression in neuronal cells. ZNF395 might play a role in transcription of PV genes and in E2-mediated repression.

UOM: 1 * 50 µG

Catalog Number: (PRSI25-823)

Supplier: ProSci Inc.

Description: FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

UOM: 1 * 50 µG

Catalog Number: (PRSI25-581)

Supplier: ProSci Inc.

Description: ZNF326 is a candidate transcription factor.

UOM: 1 * 50 µG

Catalog Number: (PRSI96-729)

Supplier: ProSci Inc.

Description: Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).

UOM: 1 * 100 µG

Catalog Number: (PRSI91-480)

Supplier: ProSci Inc.

Description: Regenerating Islet-Derived Protein 1- alpha (REG1A) belongs to the Reg family of secreted proteins with a C-type lectic domain. REG1A is highly expressed levels in fetal and infant brains, much lower in adult brains. REG1A promotes the maintenance and growth of pancreatic islet cells and intestinal villi. In addition to, REG1A Might act as an inhibitor of spontaneous calcium carbonate precipitation and be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

UOM: 1 * 50 µG

Catalog Number: (PRSI27-523)

Supplier: ProSci Inc.

Description: The SOX30 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells.

UOM: 1 * 50 µG

Catalog Number: (PRSI48-839)

Supplier: ProSci Inc.

Description: NF-IL6 is a member of the CAAT/enhancer-binding protein (C/EBP) family of transcription factors. It has been shown to directly interact with the retinoblastoma (RB) protein.

UOM: 1 * 50 µG

Catalog Number: (PRSI47-132)

Supplier: ProSci Inc.

Description: Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears tobe a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitationmay be useful in diagnosing and monitoring prostate cancer.

UOM: 1 * 100 µG

Catalog Number: (PRSI76-224)

Supplier: ProSci Inc.

Description: The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.

UOM: 1 * 0,5 mg

New Product

Catalog Number: (PRSI18-728)

Supplier: ProSci Inc.

Description: Anti-CRYBB1 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

New Product