You Searched For: PROSCI

Catalog Number: (PRSI6721P)

Supplier: ProSci Inc.

Description: PIERCE1 peptide is used for blocking the activity of PIERCE1 antibody.

UOM: 1 * 50 µG

Catalog Number: (PRSI26-185)

Supplier: ProSci Inc.

Description: PTDSS1 is a multi-pass membrane protein. It belongs to the phosphatidyl serine synthase family. PTDSS1 catalyzes a base-exchange reaction in which the polar head group of phosphatidylcholine is replaced by L-serine.

UOM: 1 * 50 µG

Catalog Number: (PRSI6237)

Supplier: ProSci Inc.

Description: ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.

UOM: 1 * 100 µG

Catalog Number: (PRSI6263)

Supplier: ProSci Inc.

Description: EZH2 Antibody: EZH2 was initially identified as a homolog of the drosophila Enhancer of Zeste through exon trap screening of chromosome 21. Both EZH2 and the related protein EZH1 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Overexpression of EZH2 has been reported as a marker for advanced and metastatic cancers.

UOM: 1 * 100 µG

Catalog Number: (PRSI46-947)

Supplier: ProSci Inc.

Description: Anti-CERS1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (PRSI46-272)

Supplier: ProSci Inc.

Description: Anti-RASIP1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (PRSI5581P)

Supplier: ProSci Inc.

Description: POU5F1 peptide is used for blocking the activity of POU5F1 antibody.

UOM: 1 * 50 µG

Catalog Number: (PRSI29-184)

Supplier: ProSci Inc.

Description: RFX4 is a transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX4 is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. RFX4 may be a transcriptional repressor rather than a transcriptional activator.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.

UOM: 1 * 50 µG

Catalog Number: (PRSI7333P)

Supplier: ProSci Inc.

Description: 19 amino acid peptide near the carboxy terminus of human APO-E.

UOM: 1 * 50 µG

Catalog Number: (PRSI42-348)

Supplier: ProSci Inc.

Description: Anti-SON Goat Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (PRSI36-131)

Supplier: ProSci Inc.

Description: TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

UOM: 1 * 100 Tests

Catalog Number: (PRSI45-566)

Supplier: ProSci Inc.

Description: Anti-FAIM Goat Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (PRSI91-534)

Supplier: ProSci Inc.

Description: EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence and migration of endothelial cells, and acts as an endothelial cell survival agent through upregulation of Bcl-2 expression. EDIL3 has also been shown to be an endogenous inhibitor of inflammatory cell recruitment by interfering with the integrin LFA-1-dependent leukocyte-endothelial adhesion. Human EDIL3 is synthesized as a precursor with a 16 amino acid signal sequence and a 464 amino acid mature chain.

UOM: 1 * 50 µG

Catalog Number: (PRSI3305)

Supplier: ProSci Inc.

Description: ARMER Antibody: Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

UOM: 1 * 100 µG

Catalog Number: (PRSI40-544)

Supplier: ProSci Inc.

Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.

UOM: 1 * 10 µG

Catalog Number: (PRSI46-669)

Supplier: ProSci Inc.

Description: Anti-GPR3 Goat Polyclonal Antibody

UOM: 1 * 100 µG