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Image Unavailable-STMC73422

Shz-1 is a cell-permeable, sulphonyl hydrazone (Shz) compound that activates cardiac differentiation through induction of genes such as Nkx2.5 (Sadek et al.).DIFFERENTIATION Promotes cardiac differentiation in mouse induced pluripotent stem cells ( 1 * 10 mg

Catalog Number: (STMC73422)
Supplier: STEMCELL TECHNOLOGIES
Description: Shz-1 is a cell-permeable, sulphonyl hydrazone (Shz) compound that activates cardiac differentiation through induction of genes such as Nkx2.5 (Sadek et al.).DIFFERENTIATION Promotes cardiac differentiation in mouse induced pluripotent stem cells ( 1 * 10 mg
UOM: 1 * 10 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-STMC73774

Purvalanol A is a cell-permeable, potent, and selective inhibitor of cyclin-dependent kinases (CDKs). CDKs and cyclins form a stoich iometric complex which is necessary for the CDK subunit to gain its protein kinase activity. It has been shown that t 1 * 10 mg

Catalog Number: (STMC73774)
Supplier: STEMCELL TECHNOLOGIES
Description: Purvalanol A is a cell-permeable, potent, and selective inhibitor of cyclin-dependent kinases (CDKs). CDKs and cyclins form a stoich iometric complex which is necessary for the CDK subunit to gain its protein kinase activity. It has been shown that t 1 * 10 mg
UOM: 1 * 10 mg

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Image Unavailable-STMC100-0891

NBQX is a neuroprotective agent and a potent and competitive AMPA receptor antagonist (IC50 = 0.15 M Sheardown et al.). AMPA recep tors are cation channels and ionotropic glutamate transmembrane receptors that play an important role in the function 1 * 10 mg

Catalog Number: (STMC100-0891)
Supplier: STEMCELL TECHNOLOGIES
Description: NBQX is a neuroprotective agent and a potent and competitive AMPA receptor antagonist (IC50 = 0.15 M Sheardown et al.). AMPA recep tors are cation channels and ionotropic glutamate transmembrane receptors that play an important role in the function 1 * 10 mg
UOM: 1 * 10 mg

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Image Unavailable-STMC27216

REVERSIBLE STRAINERS 70 M SMALL 1 * 50 items

Catalog Number: (STMC27216)
Supplier: STEMCELL TECHNOLOGIES
Description: REVERSIBLE STRAINERS 70 M SMALL 1 * 50 items
UOM: 1 * 50 items

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Image Unavailable-STMC34815

AggreWell800 24-well Plate, 5 pack 1 * 1 KIT

Catalog Number: (STMC34815)
Supplier: STEMCELL TECHNOLOGIES
Description: AggreWell800 24-well Plate, 5 pack 1 * 1 KIT
UOM: 1 * 5 items

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Image Unavailable-STMC100-0898

CP-945,598 is a selective cannabinoid type 1 (CB1) receptor antagonist (Ki = 0.7 nM) and exhibits low affinity for CB2 receptors (Ki = 7.6 M Hadcock et al.). Cannabinoid receptors are part of the G protein-coupled receptor (GPCR) superfamily, and r 1 * 10 mg

Catalog Number: (STMC100-0898)
Supplier: STEMCELL TECHNOLOGIES
Description: CP-945,598 is a selective cannabinoid type 1 (CB1) receptor antagonist (Ki = 0.7 nM) and exhibits low affinity for CB2 receptors (Ki = 7.6 M Hadcock et al.). Cannabinoid receptors are part of the G protein-coupled receptor (GPCR) superfamily, and r 1 * 10 mg
UOM: 1 * 10 mg

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Image Unavailable-STMC100-0889

Benztropine is an acetylcholine muscarinic m1 receptor antagonist (Ki = 0.59 nM Sogawa et al.) and a dopamine reuptake inhibitor (D eshmukh et al.). The pharmacological properties of benztropine can help patients manage the symptoms (e.g. tremors) o 1 * 1 g

Catalog Number: (STMC100-0889)
Supplier: STEMCELL TECHNOLOGIES
Description: Benztropine is an acetylcholine muscarinic m1 receptor antagonist (Ki = 0.59 nM Sogawa et al.) and a dopamine reuptake inhibitor (D eshmukh et al.). The pharmacological properties of benztropine can help patients manage the symptoms (e.g. tremors) o 1 * 1 g
UOM: 1 * 1 g

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Image Unavailable-STMC72854

Raloxifene is a selective estrogen receptor modulator (SERM) that exhibits agonistic (estrogenic) activity in bone cells without sti mulating ER activity in breast or uterine tissues (Black et al.).DIFFERENTIATION Enhances osteoblast differentiation 1 * 500 mg

Catalog Number: (STMC72854)
Supplier: STEMCELL TECHNOLOGIES
Description: Raloxifene is a selective estrogen receptor modulator (SERM) that exhibits agonistic (estrogenic) activity in bone cells without sti mulating ER activity in breast or uterine tissues (Black et al.).DIFFERENTIATION Enhances osteoblast differentiation 1 * 500 mg
UOM: 1 * 500 mg

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Image Unavailable-STMC100-0567

R428 is a potent and selective inhibitor of Axl (IC50 = 14 nM) with antiproliferative activity (Holland et al.). Axl is a receptor t yrosine kinase that is involved in cell survival, proliferation, adhesion, and migration (Chen et al.). R428 exhibits 1 * 10 mg

Catalog Number: (STMC100-0567)
Supplier: STEMCELL TECHNOLOGIES
Description: R428 is a potent and selective inhibitor of Axl (IC50 = 14 nM) with antiproliferative activity (Holland et al.). Axl is a receptor t yrosine kinase that is involved in cell survival, proliferation, adhesion, and migration (Chen et al.). R428 exhibits 1 * 10 mg
UOM: 1 * 10 mg

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Image Unavailable-STMC20125

RoboSep Filter Tips 1 * 8 items

Catalog Number: (STMC20125)
Supplier: STEMCELL TECHNOLOGIES
Description: RoboSep Filter Tips 1 * 8 items
UOM: 1 * 8 items

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Image Unavailable-STMC100-0553

Camostat is a serine protease inhibitor with antiviral properties (Coote et al. Hoffmann et al.). It inhibits the transmembrane ser ine protease PRSS2, which is involved in viral infections such as COVID-19 (Hoffmann et al.). This product is suppli 1 * 50 mg

Catalog Number: (STMC100-0553)
Supplier: STEMCELL TECHNOLOGIES
Description: Camostat is a serine protease inhibitor with antiviral properties (Coote et al. Hoffmann et al.). It inhibits the transmembrane ser ine protease PRSS2, which is involved in viral infections such as COVID-19 (Hoffmann et al.). This product is suppli 1 * 50 mg
UOM: 1 * 50 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-STMC100-0552

Camostat is a serine protease inhibitor with antiviral properties (Coote et al. Hoffmann et al.). It inhibits the transmembrane ser ine protease PRSS2, which is involved in viral infections such as COVID-19 (Hoffmann et al.). This product is suppli 1 * 10 mg

Catalog Number: (STMC100-0552)
Supplier: STEMCELL TECHNOLOGIES
Description: Camostat is a serine protease inhibitor with antiviral properties (Coote et al. Hoffmann et al.). It inhibits the transmembrane ser ine protease PRSS2, which is involved in viral infections such as COVID-19 (Hoffmann et al.). This product is suppli 1 * 10 mg
UOM: 1 * 10 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-STMC100-0882

(S)-Duloxetine is a thiophene derivative that potently inhibits the reuptake of serotonin (5-HT) and norepinephrine (IC50 = 28 nM an d 46 nM, respectively Kasamo et al. Soni et al. Wong et al.). It suppresses pyramidal neuronal firing in the hippo 1 * 50 mg

Catalog Number: (STMC100-0882)
Supplier: STEMCELL TECHNOLOGIES
Description: (S)-Duloxetine is a thiophene derivative that potently inhibits the reuptake of serotonin (5-HT) and norepinephrine (IC50 = 28 nM an d 46 nM, respectively Kasamo et al. Soni et al. Wong et al.). It suppresses pyramidal neuronal firing in the hippo 1 * 50 mg
UOM: 1 * 50 mg

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Image Unavailable-STMC73334

PLX4032 is an ATP-competitive inhibitor of the serine/threonine kinase B-RAF proto-oncogene, with IC values of 31 and 100 nM for t he wild type and V600E mutant forms respectively (Khazak et al. Sala et al.).CANCER RESEARCH Inhibits proliferation 1 * 50 mg

Catalog Number: (STMC73334)
Supplier: STEMCELL TECHNOLOGIES
Description: PLX4032 is an ATP-competitive inhibitor of the serine/threonine kinase B-RAF proto-oncogene, with IC values of 31 and 100 nM for t he wild type and V600E mutant forms respectively (Khazak et al. Sala et al.).CANCER RESEARCH Inhibits proliferation 1 * 50 mg
UOM: 1 * 50 mg

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Image Unavailable-STMC100-0265

GSK621 is a specific agonist of AMP-activated protein kinase (AMPK Sujobert et al.)CANCER RESEARCH Increases AMPK T172 phosphoryl ation, a marker of AMPK activation, in acute myeloid leukemia (AML) cells and primary AML samples (Sujobert et al.). 1 * 1 mg

Catalog Number: (STMC100-0265)
Supplier: STEMCELL TECHNOLOGIES
Description: GSK621 is a specific agonist of AMP-activated protein kinase (AMPK Sujobert et al.)CANCER RESEARCH Increases AMPK T172 phosphoryl ation, a marker of AMPK activation, in acute myeloid leukemia (AML) cells and primary AML samples (Sujobert et al.). 1 * 1 mg
UOM: 1 * 1 mg

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Image Unavailable-STMC27000

STEMGRID - 6 1 * 1 items

Catalog Number: (STMC27000)
Supplier: STEMCELL TECHNOLOGIES
Description: STEMGRID - 6 1 * 1 items
UOM: 1 * 1 items

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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