You Searched For: 5-Bromo-1H-indazole-7-carboxylic acid

Catalog Number: (PRSI30-359)

Supplier: ProSci Inc.

Description: The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT); and dihydrolipoyl dehydrogenase (DLD). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 100 µG

Catalog Number: (PRSI30-360)

Supplier: ProSci Inc.

Description: The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT); and dihydrolipoyl dehydrogenase (DLD). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 100 µG

Catalog Number: (PRSI27-707)

Supplier: ProSci Inc.

Description: PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

UOM: 1 * 50 µG

Catalog Number: (PRSI25-901)

Supplier: ProSci Inc.

Description: SLC16A6 is a proton-linked monocarboxylate transporter.It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

UOM: 1 * 50 µG

Supplier: MP Biomedicals

Description: Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Lactate is one of the main components of Ringer′s lactate or lactated Ringer′s solution. It is a fermentation acid from milk or carbohydrates.

Catalog Number: (PRSI27-169)

Supplier: ProSci Inc.

Description: DLD is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 50 µG

Supplier: Alfa Aesar

Description: Calcium pyruvate, anhydrous 97%

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Catalog Number: (APPC252908.1608)

Supplier: APPLICHEM

Description: A reagent for the detection of indole-positive and indole-negative microorganisms. Some microorganisms can cleave tryptophan which is especially abundant in trypticalle digested peptone to give pyruvic acid, ammonia and indole. Indole then reacts with 4-dimethylaminobenzaldehyde to form a dark red dye. As tryptophan also gives a colour reaction with 4-dimethylaminobenzaldehyde, it must be separated from the indole. This is achieved by selectively extracting indole with butanol.

UOM: 1 * 100 mL

Supplier: GE Healthcare - Hyclone

Description: DMEM Low Glucose was the original modification of Basal Medium Eagle (BME) used to grow mouse embryonic cells. DMEM, Low Glucose is suitable for the culturing of many immortalised cell lines from humans, monkeys, hamsters, rats, mice, chicken and fish. DMEM contains four times more amino acids, vitamins and other supplementary components than Basal Medium Eagle (BME), the base media from which DMEM was derived. As DMEM contains no growth-promoting agents or proteins, supplementation with FBS is recommended for optimal performance.

Catalog Number: (42327-1ML)

Supplier: Merck

Description: Organic Standard, Ethyl pyruvate, ≥97,0% (GC)

UOM: 1 * 1 mL

Catalog Number: (USBIP9545-15C)

Supplier: US Biological

Description: Anti-Pyruvate Kinase Sheep Polyclonal Antibody

UOM: 1 * 1 mg

Catalog Number: (USBIP9545-05A)

Supplier: US Biological

Description: Anti-Pyruvate Kinase Goat Polyclonal Antibody

UOM: 1 * 1 mL

Catalog Number: (ABCAAB126224-50)

Supplier: Abcam

Description: Anti-Pyruvate Dehydrogenase E2 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (EVBIEB06731)

Supplier: Everest Biotech

Description: Anti-Pyruvate dehydrogenase / PDHX Goat Polyclonal Antibody

UOM: 1 * 0,1 mg

Catalog Number: (USBI137998)

Supplier: US Biological

Description: Anti-Glutamic Pyruvic Transaminase Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (USBI131078)

Supplier: US Biological

Description: Anti-PDHK2 [Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 2, Mitochondrial, Pyruvate Dehydrogenase Kinase Isoform 2, PDH Kinase 2, PDKII, PDK2) Mouse Polyclonal Antibody

UOM: 1 * 50 µG