You Searched For: Antibodies

Catalog Number: (BOSSBS-8602R)

Supplier: Bioss

Description: GOX is a 370 amino acid protein that is expressed in liver and pancreas. HAO1 is localized to peroxisomes and aids in organic acid metabolism via 2-hydroxyacid oxidase activity. 2-hydroxyacid oxidases, such as HAO1, are enzymes that require a flavin cofactor to oxidize 2-hydroxyacids to 2-ketoacids while reducing oxygen to hydrogen peroxide. HAO1 prefenentially oxidizes the substrate glycolate and also oxidizes other substrates, including 2-hydroxy fatty acids as well as L-?hydroxy acids of moderately short chain lengths. The oxidation of glycolate yields glyoxylate which is utilized for peroxisomal synthesis of glycine. HAO1 is also able to convert glyoxylate to oxalate. HAO1 is thought to play a role in the pathophysiology of hyperoxaluria type 1, which is caused by defects in AGXT, a peroxisomal enzyme, leading to accumulation of glyoxylate. Hyperoxaluria type 1 is characterized by an accumulation of oxalate that is thought to lead to precipitates of calcium oxalate in kidneys which can be fatal.

UOM: 1 * 100 µl

Catalog Number: (USBII7661-23S)

Supplier: US Biological

Description: Anti-INSR Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Catalog Number: (USBIT9160-03A)

Supplier: US Biological

Description: Anti-TNF Rabbit Polyclonal Antibody

UOM: 1 * 500 µG

Catalog Number: (USBI044376)

Supplier: US Biological

Description: Anti-ZNF81 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Catalog Number: (USBI044116)

Supplier: US Biological

Description: Anti-ZN673 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-5180R-A488)

Supplier: Bioss

Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, ALX binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TENC1. Recruitment of GRB2 and phosphatidylinositol 3 kinase regulatory subunits by AXL leads to the downstream activation of the AKT kinase. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response. In case of filovirus infection, seems to function as a cell entry factor.

UOM: 1 * 100 µl

Catalog Number: (USBIC2254-68D)

Supplier: US Biological

Description: Anti-NCAM1 Mouse Monoclonal Antibody [clone: 123C3]

UOM: 1 * 50 µl

Catalog Number: (BOSSBS-4264R-CY7)

Supplier: Bioss

Description: May regulate transcription during sexual development.

UOM: 1 * 100 µl

Catalog Number: (USBI035252-PE)

Supplier: US Biological

Description: Anti-ETV5 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

UOM: 1 * 200 µl

Catalog Number: (ABGEAP2953B)

Supplier: Abgent

Description: Anti-GMPS Rabbit Polyclonal Antibody

UOM: 1 * 400 µl

Catalog Number: (BOSSBS-5056R-CY5.5)

Supplier: Bioss

Description: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-7553R-A750)

Supplier: Bioss

Description: Eph receptor A2 is the receptor for members of the ephrin-A family. It binds to ephrin-A1, -A3, -A4 and -A5. Eph receptor A3 is also a receptor for members of the ephrin-A family. It binds to ephrin-A2, -A3, -A4 and -A5 and is thought to play a role in lymphoid function. Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5. It binds more poorly to ephrin-A2 and -A3. It may play a role in a signal transduction process involved in hindbrain pattern formation.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-1424R-A350)

Supplier: Bioss

Description: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-10366R)

Supplier: Bioss

Description: Anti-MYPN Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Catalog Number: (ABGEAP14856C)

Supplier: Abgent

Description: Anti-GLP2R Rabbit Polyclonal Antibody

UOM: 1 * 400 µl

Catalog Number: (AVIVARP53834_P050)

Supplier: Aviva Systems Biology

Description: Anti-GSG1 Rabbit Polyclonal Antibody

UOM: 1 * 50 µG