You Searched For: Antibodies

Catalog Number: (BOSSBS-9624R-A488)

Supplier: Bioss

Description: Imp3, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

UOM: 1 * 100 µl

Catalog Number: (USBIS7965-24K2)

Supplier: US Biological

Description: Anti-Staphylococcus aureus, Enterotoxin I Mouse Monoclonal Antibody [clone: 10F460]

UOM: 1 * 200 µG

Catalog Number: (BOSSBS-4100R-CY5)

Supplier: Bioss

Description: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

UOM: 1 * 100 µl

Catalog Number: (USBI031636)

Supplier: US Biological

Description: Anti-PLIN2 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-4660R-CY3)

Supplier: Bioss

Description: This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

UOM: 1 * 100 µl

Catalog Number: (USBI039141-APC)

Supplier: US Biological

Description: Anti-NRBP1 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

UOM: 1 * 200 µl

Catalog Number: (USBIM2352-09T-BIOT)

Supplier: US Biological

Description: Anti-MAP Kinase p38, beta Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

Catalog Number: (BOSSBS-2610R-A680)

Supplier: Bioss

Description: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.

UOM: 1 * 100 µl

Catalog Number: (IMMRIR2014)

Supplier: ImmunoReagents

Description: ImmunoReagents’ Horseradish Peroxidase (HRP) antibody conjugates are the most popular conjugates due to their high level of sensitivity, stability, and low costs. HRP conjugates are an ideal choice for use in ELISA, Immunohistochemistry (IHC), and Western blotting experiments.

UOM: 1 * 0,5 mg

Catalog Number: (BOSSBS-11383R-FITC)

Supplier: Bioss

Description: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

UOM: 1 * 100 µl

Catalog Number: (USBI146733)

Supplier: US Biological

Description: Anti-KPNA2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Catalog Number: (USBI036021-PE)

Supplier: US Biological

Description: Anti-GGNBP2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

UOM: 1 * 200 µl

Catalog Number: (AVIVARP47404_P050)

Supplier: Aviva Systems Biology

Description: Anti-TMEM57 Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

Catalog Number: (BOSSBS-11209R-CY3)

Supplier: Bioss

Description: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A). Required for the proper formation of hair follicles and the control of epidermal differentiation (By similarity).

UOM: 1 * 100 µl

Catalog Number: (BOSSBS-10235R-FITC)

Supplier: Bioss

Description: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.

UOM: 1 * 100 µl

Catalog Number: (USBI042566)

Supplier: US Biological

Description: Anti-TACC1 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl