You Searched For: Fmoc-2-aminobutyric+acid

Catalog Number: (PRSI79-658)

Supplier: ProSci Inc.

Description: GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site. Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein. G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsynaptic inhibitions: presynaptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsynaptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to synaptic inhibition, GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation.

UOM: 1 * 100 µG

Supplier: BLD PHARMATECH GMBH

Description: (23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid 98%

Supplier: Novabiochem (Part of Merck)

Description: N-Fmoc-glycine

Supplier: Novabiochem (Part of Merck)

Description: Fmoc-Thi-OH

Catalog Number: (MOLE18662074-25G)

Supplier: Molekula

Description: N-Fmoc-glycine

UOM: 1 * 25 g

 This is a MarketSource item. Additional charges may apply

Supplier: Novabiochem (Part of Merck)

Description: Fmoc-Tle-OH ≥99.0% (by HPLC), Novabiochem®

Supplier: Novabiochem (Part of Merck)

Description: N-Fmoc-L-norleucine

Supplier: Novabiochem (Part of Merck)

Description: N-Fmoc-L-alanine ≥99.0% (by HPLC), Novabiochem®

Catalog Number: (MOLE72095944-5G)

Supplier: Molekula

Description: 9-Fluorenylmethyl chloroformate (Fmoc chloride)

UOM: 1 * 5 g

 This is a MarketSource item. Additional charges may apply

Catalog Number: (MOLEM11086183)

Supplier: Molekula

Description: 9-Fluorenylmethyl chloroformate (Fmoc chloride)

UOM: 1 * 25 g

 This is a MarketSource item. Additional charges may apply

Supplier: Novabiochem (Part of Merck)

Description: 9-Fluorenylmethyl chloroformate (Fmoc chloride)

Supplier: Novabiochem (Part of Merck)

Description: N-ɑ-Fmoc-N-Trityl-L-histidine, powder_white to off-white

Supplier: Alfa Aesar

Description: Fmoc-N-methyl-L-leucine 98%

Supplier: Novabiochem (Part of Merck)

Description: The base resin is PEG-PS-copoymer (90µm), functionalised with 4-hydroxy-methylphenoxyacetic acid.

Supplier: Alfa Aesar

Description: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]anthranilic acid 98%

Supplier: Novabiochem (Part of Merck)

Description: An excellent derivative for the chemoselective ligation of unprotected peptides in aqueous media via oxime formation. This derivative introduces a hydroxylamine functionality which can couple with aldehyde groups present in another peptide unit.