You Searched For: Methyl+1,4-Dioxaspiro[4.5]decane-8-carboxylate


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Supplier: Thermo Scientific
Description: Appearance: Clear colorless to yellow Liquid

Catalog Number: (BLDPBD10084-1G)
Supplier: BLD PHARMATECH GMBH
Description: 1,4-Dioxa-8-azaspiro[4.5]decane 97%
UOM: 1 * 1 g


Supplier: APOLLO SCIENTIFIC
Description: 1,4-Dioxa-8-azaspiro[4.5]decane 98%

Supplier: APOLLO SCIENTIFIC
Description: 2,2-Pentamethylene-1,3-dioxolane 95%

Supplier: BLD PHARMATECH GMBH
Description: 2,2-Pentamethylene-1,3-dioxolane 97%

Supplier: APOLLO SCIENTIFIC
Description: Nigericin sodium salt

Supplier: Cayman Chemical
Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC<sub>50</sub> = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.

Catalog Number: (MOLEM65975104)
Supplier: Molekula
Description: 1,4-Dioxaspiro[4.5]decan-8-one
UOM: 1 * 25 g

Market Source Item This is a MarketSource item. Additional charges may apply

Supplier: APOLLO SCIENTIFIC
Description: 6,10-Dioxaspiro[4.5]decane-7,9-dione 95%

Supplier: APOLLO SCIENTIFIC
Description: 1-[8-(3,4-Dimethoxyphenyl)-1,4-dioxaspiro[4.5]dec-8-yl]methanamine

Catalog Number: (APOSOR303181-500MG)
Supplier: APOLLO SCIENTIFIC
Description: (2E)-3-{1,4-Dioxaspiro[4.5]dec-7-en-7-yl}prop-2-enoic acid
UOM: 1 * 500 mg


Supplier: APOLLO SCIENTIFIC
Description: [8-(3-Methylphenyl)-1,4-dioxaspiro[4.5]dec-8-yl]methylamine

Catalog Number: (APOSPC510080-1G)
Supplier: APOLLO SCIENTIFIC
Description: 1-[8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]dec-8-yl]methanamine
UOM: 1 * 1 g


Catalog Number: (APOSOR470282-5G)
Supplier: APOLLO SCIENTIFIC
Description: (8-Phenyl-1,4-dioxaspiro[4.5]dec-8-yl)methanamine
UOM: 1 * 5 g


Catalog Number: (APOSOR13174-25G)
Supplier: APOLLO SCIENTIFIC
Description: 4,4,5,5-Tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1,3,2-dioxaborolane
UOM: 1 * 25 g


Catalog Number: (APOSOR14268-1G)
Supplier: APOLLO SCIENTIFIC
Description: 5-Bromo-3-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole
UOM: 1 * 1 g


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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