You Searched For: PROSCI

Catalog Number: (PRSI76-566)

Supplier: ProSci Inc.

Description: Anti-Ptprc Mouse Monoclonal Antibody [clone: 104] (APC (Allophycocyanin)-Cy7®)

UOM: 1 * 0,025 mg

New Product

Catalog Number: (PRSI4679P)

Supplier: ProSci Inc.

Description: SATB1 peptide is used for blocking the activity of SATB1 antibody.

UOM: 1 * 50 µG

Catalog Number: (PRSI92-176)

Supplier: ProSci Inc.

Description: ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumour cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumour formation, as demonstrated by shRNA knockdown experiments.

UOM: 1 * 50 µG

Catalog Number: (PRSI49-800)

Supplier: ProSci Inc.

Description: Beta 2-microglobulin is the low molecular weight component of HLA antigens and as such is involved in the presentation of endogenous antigens, activation of T lymphocytes and functional emergence of natural killer cells. It is found in the serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning and other conditions leading renal tubular dysfunction. ESTs have been isolated from libraries generated using virtually every tissue in the body.

UOM: 1 * 50 µl

Catalog Number: (PRSI24-235)

Supplier: ProSci Inc.

Description: Anti-IFNG Recombinant Antibody [Clone: D9D10]

UOM: 1 * 0,2 mg

New Product

Catalog Number: (PRSI61-637)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI5717)

Supplier: ProSci Inc.

Description: APC1 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.

UOM: 1 * 100 µG

Catalog Number: (PRSIXPS-1033)

Supplier: ProSci Inc.

Description: Tyrosine Hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons. We raised this polyclonal antibody against a peptide representing the sequence around Ser40 in rat TH. This antibody is suitable for most immunochemical applications in a variety of mammalian and some non-mammalian species.

UOM: 1 * 100 µl

Catalog Number: (PRSI7623)

Supplier: ProSci Inc.

Description: The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer. The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary.

UOM: 1 * 100 µG

Catalog Number: (PRSI62-043)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50. For FACS starting dilution is: 1:10~50.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI27-364)

Supplier: ProSci Inc.

Description: Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.

UOM: 1 * 100 µG

Catalog Number: (PRSI38-147)

Supplier: ProSci Inc.

Description: A family of resistin-like molecules (RELMs) has been identified in rodents and humans. RELM alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM alpha and RELM beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain. RELM alpha and Resistin are secreted exclusively by adipocytes while RELM beta is expressed in the epithelium of the colon and small bowel. The RELMs together with resistin comprise a class of tissue-specific signaling molecules. The physiological role and molecular targets of RELM alpha are still unknown.

UOM: 1 * 100 µG

Catalog Number: (PRSI5057)

Supplier: ProSci Inc.

Description: FNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.

UOM: 1 * 100 µG

Catalog Number: (PRSI54-313)

Supplier: ProSci Inc.

Description: Anti-GCG Rabbit Monoclonal Antibody

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI90-229)

Supplier: ProSci Inc.

Description: APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumour cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. MultimericAPRIL™ is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the NH2 terminus of APRIL is required for binding to negatively charged sulphated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumour cells as well as primary lymphoid cells.

UOM: 1 * 10 µG

Catalog Number: (PRSI27-388)

Supplier: ProSci Inc.

Description: ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. Transcriptional activation by ERR3 can be ligand-independent.

UOM: 1 * 100 µG