You Searched For: PROSCI

Catalog Number: (PRSI33-190)

Supplier: ProSci Inc.

Description: This antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-194)

Supplier: ProSci Inc.

Description: This antibody recognises a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI33-195)

Supplier: ProSci Inc.

Description: This antibody recognises a protein of 205 kDa-220 kDa, identified as CD45RA, an isoform of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ Tcells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin Tcells. T-cells expressing CD45RO are memory Tcells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral Tcells. This CD45RA antibody is useful in the study of the subpopulation of CD4+ or CD8+ T-cells. It is especially useful in differentiating T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI23-693)

Supplier: ProSci Inc.

Description: Anti-ALDH7A1 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

New Product

Catalog Number: (PRSI23-674)

Supplier: ProSci Inc.

Description: Anti-ERBB2IP Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

New Product

Catalog Number: (PRSI23-671)

Supplier: ProSci Inc.

Description: Anti-MEMO1 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

New Product

Catalog Number: (PRSI33-284)

Supplier: ProSci Inc.

Description: CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. [Wiki].

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI33-315)

Supplier: ProSci Inc.

Description: This mAb recognises a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This mAb is excellent for staining of formalin-fixed tissues.

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI33-299)

Supplier: ProSci Inc.

Description: CD45RA is an isoform of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI33-300)

Supplier: ProSci Inc.

Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterised by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage.

UOM: 1 * 100 µG

New Product

Catalog Number: (PRSI62-650)

Supplier: ProSci Inc.

Description: For IHC-P starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50. For WB starting dilution is: 1:1000. For IP starting dilution is: 1:500~1000.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI62-671)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI62-665)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI62-667)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI63-106)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

UOM: 1 * 400 µl

New Product

Catalog Number: (PRSI63-122)

Supplier: ProSci Inc.

Description: For IHC-P starting dilution is: 1:10~50. For WB starting dilution is: 1:1000. For IF starting dilution is: 1:10~50.

UOM: 1 * 400 µl

New Product